Frizzled-10 is a protein in humans that is encoded by FZD10 gene. Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
The following FZD10 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
FZD10 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA009104GA01HU | FZD10 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA005299 | FZD10 Antibody |
Human,Mouse | WB, ELISA |
CSB-PA006791 | FZD10 Antibody |
Human,Mouse,Monkey | WB, IHC, IF, ELISA |
CSB-PA970487 | FZD10 Antibody |
Human,Mouse | ELISA,IHC |
CSB-PA891782LA01HU | FZD10 Antibody |
Human | ELISA, WB, IHC, IF |
CSB-PA891782LC01HU | FZD10 Antibody, FITC conjugated |
Human | |
CSB-PA891782LD01HU | FZD10 Antibody, Biotin conjugated |
Human | ELISA |
FZD10 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF803892MO | Recombinant Mouse Frizzled-10 (Fzd10) |
in vitro E.coli expression system |
CSB-YP803892MO1 CSB-EP803892MO1 CSB-BP803892MO1 CSB-MP803892MO1 CSB-EP803892MO1-B |
Recombinant Mouse Frizzled-10 (Fzd10), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FZD10 Proteins for Gallus gallus (Chicken)
Code | Product Name | Source |
---|---|---|
CSB-CF886116CH | Recombinant Chicken Frizzled-10 (FZD10) |
in vitro E.coli expression system |
CSB-YP886116CH1 CSB-EP886116CH1 CSB-BP886116CH1 CSB-MP886116CH1 CSB-EP886116CH1-B |
Recombinant Chicken Frizzled-10 (FZD10), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FZD10 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF891782HU | Recombinant Human Frizzled-10 (FZD10) |
in vitro E.coli expression system |
CSB-YP891782HU1 CSB-EP891782HU1 CSB-BP891782HU1 CSB-MP891782HU1 CSB-EP891782HU1-B |
Recombinant Human Frizzled-10 (FZD10), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |