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Gamma-aminobutyric acid receptor-associated protein-like 2 is a protein in humans that is encoded by GABARAPL2 gene. Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
The following GABARAPL2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
GABARAPL2 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA03484A0Rb | GABARAPL2 Antibody |
Human, Rat | ELISA, WB, IHC |
| CSB-PA03484D0Rb | GABARAPL2 Antibody, Biotin conjugated |
Human | ELISA |
| CSB-PA03485A0Rb | GABARAPL2 Antibody |
Human | ELISA, WB |
| CSB-PA03485D0Rb | GABARAPL2 Antibody, Biotin conjugated |
Human | ELISA |
| CSB-PA009132GA01HU | GABARAPL2 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
GABARAPL2 Proteins for Rattus norvegicus (Rat)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP009132RA CSB-EP009132RA CSB-BP009132RA CSB-MP009132RA CSB-EP009132RA-B |
Recombinant Rat Gamma-aminobutyric acid receptor-associated protein-like 2 (Gabarapl2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GABARAPL2 Proteins for Bos taurus (Bovine)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP009132BO CSB-EP009132BO CSB-BP009132BO CSB-MP009132BO CSB-EP009132BO-B |
Recombinant Bovine Gamma-aminobutyric acid receptor-associated protein-like 2 (GABARAPL2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GABARAPL2 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP009132MO CSB-EP009132MO CSB-BP009132MO CSB-MP009132MO CSB-EP009132MO-B |
Recombinant Mouse Gamma-aminobutyric acid receptor-associated protein-like 2 (Gabarapl2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GABARAPL2 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP009132HU CSB-EP009132HU CSB-BP009132HU CSB-MP009132HU CSB-EP009132HU-B |
Recombinant Human Gamma-aminobutyric acid receptor-associated protein-like 2 (GABARAPL2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP009132HU | Recombinant Human Gamma-aminobutyric acid receptor-associated protein-like 2 (GABARAPL2) |
E.coli |
Gamma-aminobutyric acid receptor-associated protein-like 2 is a protein in humans that is encoded by the GABARAPL2 gene. The GABARAPL2 protein is a ubiquitin-like modifier involved in intra-Golgi traffic. It modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. GABARAPL2 first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). It is involved in autophagy and plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane. The GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
