GABARAPL2 Research Reagents

Gamma-aminobutyric acid receptor-associated protein-like 2 is a protein in humans that is encoded by GABARAPL2 gene. Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.

The following GABARAPL2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

GABARAPL2 Antibodies

GABARAPL2 Antibodies for Homo sapiens (Human)

GABARAPL2 Proteins

GABARAPL2 Proteins for Rattus norvegicus (Rat)

GABARAPL2 Proteins for Bos taurus (Bovine)

GABARAPL2 Proteins for Mus musculus (Mouse)

GABARAPL2 Proteins for Homo sapiens (Human)

GABARAPL2 Background

Gamma-aminobutyric acid receptor-associated protein-like 2 is a protein in humans that is encoded by the GABARAPL2 gene. The GABARAPL2 protein is a ubiquitin-like modifier involved in intra-Golgi traffic. It modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. GABARAPL2 first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). It is involved in autophagy and plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane. The GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.

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