GPR4

GPR4, also known as G protein-coupled receptor 4, is a proton-sensing G protein-coupled receptor. It has no widely recognized common aliases. Functionally, GPR4 senses extracellular pH changes and activates downstream G proteins. It is involved in the cAMP signaling pathway, where its activation can lead to an increase in cAMP levels.
GPR4 has been associated with various diseases, including cancer and inflammatory disorders. In cancer, it may contribute to tumor progression. Currently, research on drugs targeting GPR4 is in the pre - clinical stage, with efforts focused on developing agonists or antagonists to modulate its activity for therapeutic purposes.

Popular Product:

GPR4 Antibody (CSB-PA009813LA01HU)

Validated Data

Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA009813LA01HU at dilution of 1:100

Immunofluorescent analysis of A549 cells using CSB-PA009813LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

The following GPR4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

GPR4 Antibodies

GPR4 Proteins

GPR4 Antibodies

GPR4 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA009813LA01HU	GPR4 Antibody	Human	ELISA, IHC, IF
CSB-PA009813LB01HU	GPR4 Antibody, HRP conjugated	Human	ELISA
CSB-PA009813LC01HU	GPR4 Antibody, FITC conjugated	Human
CSB-PA009813LD01HU	GPR4 Antibody, Biotin conjugated	Human	ELISA

GPR4 Proteins

GPR4 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-CF629692BO	Recombinant Bovine G-protein coupled receptor 4 (GPR4)	in vitro E.coli expression system
CSB-YP629692BO1 CSB-EP629692BO1 CSB-BP629692BO1 CSB-MP629692BO1 CSB-EP629692BO1-B	Recombinant Bovine G-protein coupled receptor 4 (GPR4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPR4 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-CF009813HU	Recombinant Human G-protein coupled receptor 4 (GPR4)	in vitro E.coli expression system
CSB-YP009813HU1 CSB-EP009813HU1 CSB-BP009813HU1 CSB-MP009813HU1 CSB-EP009813HU1-B	Recombinant Human G-protein coupled receptor 4 (GPR4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPR4 Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-CF009813PI	Recombinant Pig G-protein coupled receptor 4 (GPR4)	in vitro E.coli expression system
CSB-YP009813PI1 CSB-EP009813PI1 CSB-BP009813PI1 CSB-MP009813PI1 CSB-EP009813PI1-B	Recombinant Pig G-protein coupled receptor 4 (GPR4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

GPR4 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-CF807408MO	Recombinant Mouse G-protein coupled receptor 4 (Gpr4)	in vitro E.coli expression system
CSB-YP807408MO1 CSB-EP807408MO1 CSB-BP807408MO1 CSB-MP807408MO1 CSB-EP807408MO1-B	Recombinant Mouse G-protein coupled receptor 4 (Gpr4), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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