Probable E3 ubiquitin-protein ligase HERC1 is a protein in humans that is encoded by HERC1 gene. Involved in membrane trafficking via some guanine nucleotide exchange factor (GEF) activity and its ability to bind clathrin. Acts as a GEF for Arf and Rab, by exchanging bound GDP for free GTP. Binds phosphatidylinositol 4,5-bisphosphate, which is required for GEF activity. May also act as a E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
The following HERC1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
HERC1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA613601ZA01HU | HERC1 Antibody |
Homo sapiens | ELISA, WB (ensure identification of antigen) |
HERC1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP613601HU CSB-BP613601HU CSB-MP613601HU CSB-EP613601HU-B |
Recombinant Human Probable E3 ubiquitin-protein ligase HERC1 (HERC1), partial |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP613601HU | Recombinant Human Probable E3 ubiquitin-protein ligase HERC1 (HERC1), partial |
E.coli |