HLA-A

The HLA - A gene encodes the major histocompatibility complex, class I, A protein, commonly known as HLA - A antigen. It is also sometimes referred to as MHC class I antigen HLA - A. This protein plays a crucial role in the immune system. It binds to peptide fragments derived from pathogens and presents them on the cell surface for recognition by T - cells, initiating an immune response.
HLA - A is involved in the antigen - presentation pathway. Abnormalities in HLA - A are associated with various autoimmune diseases and some viral infections. In terms of drug development, research is focusing on using HLA - A as a target to design immunotherapies, aiming to enhance the body's immune response against specific diseases.

Validated Data

Western Blot
Positive WB detected in: A549 whole cell lysate(30µg), HEK293 whole cell lysate(30µg), HepG2 whole cell lysate(30µg), PC-3 whole cell lysate(30µg)
All lanes: HLA-A antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 41 kDa
Observed band size: 41 kDa
Exposure time: 2min

Overlay Peak curve showing jurkat cells stained with CSB-RA977288A0HU (red line) at 1:100. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100 for 10min. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*10⁶cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 35min at 4℃.Control antibody (green line) was Rabbit IgG (1ug/1*10⁶cells) used under the same conditions. Acquisition of >10,000 events was performed.

The following HLA-A reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

HLA-A Antibodies

HLA-A Proteins

HLA-A Antibodies

HLA-A Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA328989ZA01HU	HLA-A Antibody	Homo sapiens	ELISA, WB (ensure identification of antigen)
CSB-RA977288A0HU	HLA-A Recombinant Monoclonal Antibody	Human	ELISA, WB, FC

HLA-A Proteins

HLA-A Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP318036HU CSB-EP318036HU CSB-BP318036HU CSB-MP318036HU CSB-EP318036HU-B	Recombinant Human HLA class I histocompatibility antigen, A-32 alpha chain (HLA-A), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP318407HU CSB-EP318407HU CSB-BP318407HU CSB-MP318407HU CSB-EP318407HU-B	Recombinant Human HLA class I histocompatibility antigen, A-11 alpha chain (HLA-A), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP319883HU CSB-EP319883HU CSB-BP319883HU CSB-MP319883HU CSB-EP319883HU-B	Recombinant Human HLA class I histocompatibility antigen, A-69 alpha chain (HLA-A), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP322266HU CSB-EP322266HU CSB-BP322266HU CSB-MP322266HU CSB-EP322266HU-B	Recombinant Human HLA class I histocompatibility antigen, A-33 alpha chain (HLA-A), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP323682HU CSB-EP323682HU CSB-BP323682HU CSB-MP323682HU CSB-EP323682HU-B	Recombinant Human HLA class I histocompatibility antigen, A-31 alpha chain (HLA-A), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP325409HU CSB-EP325409HU CSB-BP325409HU CSB-MP325409HU CSB-EP325409HU-B	Recombinant Human HLA class I histocompatibility antigen, A-30 alpha chain (HLA-A), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP325985HU CSB-EP325985HU CSB-BP325985HU CSB-MP325985HU CSB-EP325985HU-B	Recombinant Human HLA class I histocompatibility antigen, A-25 alpha chain (HLA-A), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP326974HU CSB-EP326974HU CSB-BP326974HU CSB-MP326974HU CSB-EP326974HU-B	Recombinant Human HLA class I histocompatibility antigen, A-36 alpha chain (HLA-A), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP328989HU CSB-MP328989HU CSB-EP328989HU-B	Recombinant Human HLA class I histocompatibility antigen, A alpha chain (HLA-A), partial	Yeast Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP328994HU CSB-EP328994HU CSB-BP328994HU CSB-MP328994HU CSB-EP328994HU-B	Recombinant Human HLA class I histocompatibility antigen, A-29 alpha chain (HLA-A), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP329996HU CSB-EP329996HU CSB-BP329996HU CSB-MP329996HU CSB-EP329996HU-B	Recombinant Human HLA class I histocompatibility antigen, A-34 alpha chain (HLA-A), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP333529HU CSB-EP333529HU CSB-BP333529HU CSB-MP333529HU CSB-EP333529HU-B	Recombinant Human HLA class I histocompatibility antigen, A-26 alpha chain (HLA-A), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP335547HU CSB-EP335547HU CSB-BP335547HU CSB-MP335547HU CSB-EP335547HU-B	Recombinant Human HLA class I histocompatibility antigen, A-23 alpha chain (HLA-A), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP335548HU CSB-EP335548HU CSB-BP335548HU CSB-MP335548HU CSB-EP335548HU-B	Recombinant Human HLA class I histocompatibility antigen, A-74 alpha chain (HLA-A), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP339100HU CSB-EP339100HU CSB-BP339100HU CSB-MP339100HU CSB-EP339100HU-B	Recombinant Human HLA class I histocompatibility antigen, A-66 alpha chain (HLA-A), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP341151HU CSB-EP341151HU CSB-BP341151HU CSB-MP341151HU CSB-EP341151HU-B	Recombinant Human HLA class I histocompatibility antigen, A-43 alpha chain (HLA-A), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP356256HU CSB-EP356256HU CSB-BP356256HU CSB-MP356256HU CSB-EP356256HU-B	Recombinant Human HLA class I histocompatibility antigen, A-3 alpha chain (HLA-A), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP360790HU CSB-EP360790HU CSB-BP360790HU CSB-MP360790HU CSB-EP360790HU-B	Recombinant Human HLA class I histocompatibility antigen, A-2 alpha chain (HLA-A), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP361548HU CSB-EP361548HU CSB-BP361548HU CSB-MP361548HU CSB-EP361548HU-B	Recombinant Human HLA class I histocompatibility antigen, A-24 alpha chain (HLA-A), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP365680HU CSB-EP365680HU CSB-BP365680HU CSB-MP365680HU CSB-EP365680HU-B	Recombinant Human HLA class I histocompatibility antigen, A-68 alpha chain (HLA-A), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP600599HU CSB-EP600599HU CSB-BP600599HU CSB-MP600599HU CSB-EP600599HU-B	Recombinant Human HLA class I histocompatibility antigen, A-80 alpha chain (HLA-A), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP328989HU	Recombinant Human HLA class I histocompatibility antigen, A alpha chain (HLA-A), partial	E.coli
CSB-EP328989HUb1	Recombinant Human HLA class I histocompatibility antigen, A alpha chain (HLA-A), partial	E.coli
CSB-BP328989HU	Recombinant Human HLA class I histocompatibility antigen, A alpha chain (HLA-A), partial	Baculovirus

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HLA-A

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