HLA class II histocompatibility antigen, DRB1-3 chain is a protein in humans that is encoded by HLA-DRB1 gene. Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route; where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules; and for this reason this antigen presentation pathway is usually referred to as exogenous.
The following HLA-DRB1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
HLA-DRB1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA17949A0Rb | HLA-DRB1 Antibody |
Human | ELISA |
CSB-PA19179A0Rb | HLA-DRB1 Antibody |
Human | ELISA, WB, IF |
CSB-PA19179D0Rb | HLA-DRB1 Antibody, Biotin conjugated |
Human | ELISA |
CSB-PA361230ZA01HU | HLA-DRB1 Antibody |
Homo sapiens | ELISA, WB (ensure identification of antigen) |
CSB-PA846484ZA01HU | HLA-DRB1 Antibody |
Homo sapiens | ELISA, WB (ensure identification of antigen) |
HLA-DRB1 Proteins for Homo sapiens (Human)