HSP90B1

HSP90B1, also known as heat shock protein 90 beta 1, is a molecular chaperone. Commonly referred to as gp96, it is involved in protein folding, stabilization, and maturation. It functions by interacting with client proteins and assisting them in attaining their proper conformation. The protein participates in the unfolded protein response pathway and Toll - like receptor signaling.
HSP90B1 is associated with various diseases, including cancer and autoimmune disorders. In cancer, it can promote tumor cell survival and metastasis. Regarding drug development, it has emerged as a promising therapeutic target. Some HSP90 inhibitors are in pre - clinical and clinical trials, aiming to disrupt its function and combat related diseases.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-RP108894h could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) HSP90B1.

HSP90B1 Antibody (CSB-PA002347)

Validated Data

Western Blot analysis of HeLa cells using Endoplasmin Polyclonal Antibody

Western Blot analysis of K562 cells using Endoplasmin Polyclonal Antibody

Human Heat Shock Protein glycoprotein 96,HSP gp96 ELISA Kit (CSB-E08551h)

Validated Data

Code: CSB-E08551h

Size: 96T,5×96T,10×96T

Sensitivity: 0.156 ng/mL

Detection Range: 0.625 ng/mL-40 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following HSP90B1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

HSP90B1 Antibodies

HSP90B1 Proteins

HSP90B1 ELISA Kits

HSP90B1 Antibodies

HSP90B1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA010814GA01HU	HSP90B1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA10887A0Rb	HSP90B1 Antibody	Human	ELISA, WB, IHC, IF
CSB-PA10887C0Rb	HSP90B1 Antibody, FITC conjugated	Human
CSB-PA002347	HSP90B1 Antibody	Human,Mouse	WB, IHC, IF, ELISA
CSB-PA179036	HSP90B1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA088395	HSP90B1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC

HSP90B1 Proteins

HSP90B1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP010814HU CSB-BP010814HU CSB-MP010814HU CSB-EP010814HU-B	Recombinant Human Endoplasmin (HSP90B1)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP010814HU1	Recombinant Human Endoplasmin (HSP90B1), partial	E.coli

HSP90B1 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Source
CSB-YP010814DO CSB-EP010814DO CSB-BP010814DO CSB-MP010814DO CSB-EP010814DO-B	Recombinant Dog Endoplasmin (HSP90B1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HSP90B1 Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-YP010814CH CSB-EP010814CH CSB-BP010814CH CSB-MP010814CH CSB-EP010814CH-B	Recombinant Chicken Endoplasmin (HSP90B1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HSP90B1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP010814MO CSB-EP010814MO CSB-BP010814MO CSB-MP010814MO CSB-EP010814MO-B	Recombinant Mouse Endoplasmin (Hsp90b1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HSP90B1 Proteins for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Source
CSB-YP010814RB CSB-EP010814RB CSB-BP010814RB CSB-MP010814RB CSB-EP010814RB-B	Recombinant Rabbit Endoplasmin (HSP90B1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HSP90B1 Proteins for Mesocricetus auratus (Golden hamster)

Code	Product Name	Source
CSB-YP010814MRG CSB-EP010814MRG CSB-BP010814MRG CSB-MP010814MRG CSB-EP010814MRG-B	Recombinant Mesocricetus auratus Endoplasmin (HSP90B1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HSP90B1 Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP641820PI CSB-EP641820PI CSB-BP641820PI CSB-MP641820PI CSB-EP641820PI-B	Recombinant Pig Endoplasmin (HSP90B1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HSP90B1 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Code	Product Name	Source
CSB-YP703101MOV CSB-EP703101MOV CSB-BP703101MOV CSB-MP703101MOV CSB-EP703101MOV-B	Recombinant Macaca fascicularis Endoplasmin (HSP90B1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HSP90B1 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP714884RA CSB-EP714884RA CSB-BP714884RA CSB-MP714884RA CSB-EP714884RA-B	Recombinant Rat Endoplasmin (Hsp90b1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HSP90B1 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Code	Product Name	Source
CSB-YP716064PYX CSB-EP716064PYX CSB-BP716064PYX CSB-MP716064PYX CSB-EP716064PYX-B	Recombinant Pongo abelii Endoplasmin (HSP90B1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HSP90B1 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP839213BO CSB-EP839213BO CSB-BP839213BO CSB-MP839213BO CSB-EP839213BO-B	Recombinant Bovine Endoplasmin (HSP90B1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

HSP90B1 ELISA Kit

HSP90B1 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E08551h	Human Heat Shock Protein glycoprotein 96,HSP gp96 ELISA Kit	serum, plasma, tissue homogenates	0.156 ng/mL

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HSP90B1

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