Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]is a protein in humans that is encoded by ITGA7 gene. Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.
The following ITGA7 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
ITGA7 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA000073 | Cleaved-ITGA7 (E959) Antibody | Human,Monkey | WB, ELISA |
CSB-PA066101 | ITGA7 Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA618797LA01HU | ITGA7 Antibody | Human | ELISA, IF |
CSB-PA618797LB01HU | ITGA7 Antibody, HRP conjugated | Human | ELISA |
CSB-PA618797LC01HU | ITGA7 Antibody, FITC conjugated | Human | |
CSB-PA618797LD01HU | ITGA7 Antibody, Biotin conjugated | Human | ELISA |
ITGA7 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP618797HU CSB-EP618797HU CSB-BP618797HU CSB-MP618797HU CSB-EP618797HU-B |
Recombinant Human Integrin alpha-7 (ITGA7), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ITGA7 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP723425MO CSB-EP723425MO CSB-BP723425MO CSB-MP723425MO CSB-EP723425MO-B |
Recombinant Mouse Integrin alpha-7 (Itga7), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ITGA7 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP723566RA CSB-EP723566RA CSB-BP723566RA CSB-MP723566RA CSB-EP723566RA-B |
Recombinant Rat Integrin alpha-7 (Itga7), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |