KIR2DS2, also known as Killer cell immunoglobulin-like receptor 2DS2, is a membrane protein belonging to the killer cell immunoglobulin-like receptor (KIR) family. It is also commonly referred to as CD158j. This protein plays a crucial role in the immune system by recognizing specific HLA-C ligands on target cells, thereby modulating natural killer (NK) cell activation. It is involved in the NK cell-mediated cytotoxicity pathway.
KIR2DS2 has been associated with various diseases, including certain autoimmune disorders and infectious diseases. In the field of drug development, research is underway to explore the potential of targeting KIR2DS2 for immunotherapy, aiming to enhance immune responses against tumors and infectious agents.
KIR2DS2 Antibody (CSB-PA012360LA01HU)
Validated Data
Immunohistochemistry of paraffin-embedded human lymph node tissue using CSB-PA012360LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA012360LA01HU at dilution of 1:100
Immunofluorescent analysis of A549 cells using CSB-PA012360LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
The following KIR2DS2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
KIR2DS2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA012360LA01HU | KIR2DS2 Antibody | Human | ELISA, IHC, IF |
CSB-PA012360LB01HU | KIR2DS2 Antibody, HRP conjugated | Human | ELISA |
CSB-PA012360LC01HU | KIR2DS2 Antibody, FITC conjugated | Human | |
CSB-PA012360LD01HU | KIR2DS2 Antibody, Biotin conjugated | Human | ELISA |
KIR2DS2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF012360HU | Recombinant Human Killer cell immunoglobulin-like receptor 2DS2 (KIR2DS2) | in vitro E.coli expression system |
CSB-YP012360HU1 CSB-EP012360HU1 CSB-BP012360HU1 CSB-MP012360HU1 CSB-EP012360HU1-B |
Recombinant Human Killer cell immunoglobulin-like receptor 2DS2 (KIR2DS2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |