MFAP5, also known as Microfibrillar-associated protein 5, is a crucial extracellular matrix protein. It is also commonly referred to as MAGP-2. MFAP5 is involved in the assembly of microfibrils and interacts with fibrillin and latent TGF-β binding proteins. It participates in the TGF-β signaling pathway, regulating cell growth, differentiation, and migration.
Dysregulation of MFAP5 has been linked to various diseases, including Marfan syndrome and cancer. In drug development, targeting MFAP5 could potentially lead to new treatments for these conditions. Current research is exploring how to modulate its function to interfere with disease - related signaling cascades.
Recombinant Human Microfibrillar-associated protein 5 (MFAP5) (CSB-EP623799HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Validated Data
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA701502(MFAP5 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA701502(MFAP5 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
Human Microfibrillar-associated protein 5(MFAP5) ELISA kit (CSB-EL013750HU)
Validated Data
Code: CSB-EL013750HU
Size: 96T,5×96T,10×96T
Sensitivity: 3.125pg/ml
Detection Range: 12.5pg/ml - 800pg/ml
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following MFAP5 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
MFAP5 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA013750GA01HU | MFAP5 Antibody | Human | ELISA,WB,IHC |
CSB-PA623799LA01HU | MFAP5 Antibody | Human | ELISA, IHC |
CSB-PA701502 | MFAP5 Antibody | Human | ELISA,IHC |
MFAP5 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP623799HU CSB-BP623799HU CSB-MP623799HU CSB-EP623799HU-B |
Recombinant Human Microfibrillar-associated protein 5 (MFAP5) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP623799HU | Recombinant Human Microfibrillar-associated protein 5 (MFAP5) | E.coli |
MFAP5 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL013750HU | Human Microfibrillar-associated protein 5(MFAP5) ELISA kit | serum, plasma, tissue homogenates | 3.125pg/ml |