NCL protein (Nucleolin) is a widely distributed protein found in the cell nucleus. It is associated with chromatin within the nucleolus and pre-nucleolar ribosomal particles. NCL induces chromatin decondensation by binding with histone H1. It is believed to play a role in rRNA precursor transcription and ribosome assembly, and may also be involved in transcription elongation processes. NCL participates in various biological processes within the cell nucleus, including ribosome biogenesis, gene expression regulation, cell proliferation, and growth. NCL's involvement in cell proliferation and growth suggests a potential connection to the regulation of the cell cycle and signal transduction. This protein has garnered significant attention due to its multifunctionality in the cell nucleus and is considered a potential target for therapeutic strategies, given its likely roles in cellular functions and diseases.
Recombinant Human Nucleolin (NCL), partial
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP015535HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) NCL.
Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP015535HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) NCL.
The following NCL reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
NCL Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA015535GA01HU | NCL Antibody |
Human,Mouse | ELISA,WB,IHC |
CSB-PA015535DSR2HU | NCL Antibody |
Human | ELISA, WB, IHC |
CSB-PA015535DSR1HU | NCL Antibody |
Human | ELISA, WB |
NCL Antibodies for Arabidopsis thaliana (Mouse-ear cress)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA797796XA01DOA | NCL Antibody |
Arabidopsis thaliana | ELISA, WB (ensure identification of antigen) |
NCL Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP015535RA CSB-EP015535RA CSB-BP015535RA CSB-MP015535RA CSB-EP015535RA-B |
Recombinant Rat Nucleolin (Ncl) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NCL Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP015535HU | Recombinant Human Nucleolin (NCL),Partial |
Yeast |
CSB-EP015535HU CSB-BP015535HU CSB-MP015535HU CSB-EP015535HU-B |
Recombinant Human Nucleolin (NCL), partial |
E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NCL Proteins for Gallus gallus (Chicken)
Code | Product Name | Source |
---|---|---|
CSB-YP015535CH CSB-EP015535CH CSB-BP015535CH CSB-MP015535CH CSB-EP015535CH-B |
Recombinant Chicken Nucleolin (NCL), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NCL Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP015535MO CSB-EP015535MO CSB-BP015535MO CSB-MP015535MO CSB-EP015535MO-B |
Recombinant Mouse Nucleolin (Ncl), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NCL Proteins for Xenopus laevis (African clawed frog)
Code | Product Name | Source |
---|---|---|
CSB-YP015535XBE CSB-EP015535XBE CSB-BP015535XBE CSB-MP015535XBE CSB-EP015535XBE-B |
Recombinant Xenopus laevis Nucleolin (ncl), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NCL Proteins for Mesocricetus auratus (Golden hamster)
Code | Product Name | Source |
---|---|---|
CSB-YP015535MRG CSB-EP015535MRG CSB-BP015535MRG CSB-MP015535MRG CSB-EP015535MRG-B |
Recombinant Mesocricetus auratus Nucleolin (NCL), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NCL Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Code | Product Name | Source |
---|---|---|
CSB-YP015535MOV CSB-EP015535MOV CSB-BP015535MOV CSB-MP015535MOV CSB-EP015535MOV-B |
Recombinant Macaca fascicularis Nucleolin (NCL), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NCL Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Code | Product Name | Source |
---|---|---|
CSB-YP015535PYX CSB-EP015535PYX CSB-BP015535PYX CSB-MP015535PYX CSB-EP015535PYX-B |
Recombinant Pongo abelii Nucleolin (NCL), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NCL ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL015535HU | Human Nucleolin(NCL) ELISA kit |
serum, plasma, tissue homogenates, cell lysates | 7.81 pg/mL |