NMT1

NMT1 is an N-myristoyltransferase that primarily participates in the N-myristoylation modification process of proteins. This modification is crucial for protein localization and function, affecting their distribution within cells and interactions with other molecules. Additionally, NMT1 has been found to be overexpressed in various cancers, correlating with poor prognosis. Studies have shown that overexpression of NMT1 can promote the proliferation and growth of tumor cells, making it a potential therapeutic target for cancer treatment. Through its N-myristoylation activity, NMT1 is involved in regulating multiple signal transduction processes.

Popular Product:

NMT1 Antibody

Validated Data

SDS

Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human kidney tissue, Primary antibody: CSB-PA904948(NMT1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes

IHC

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA904948(NMT1 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200)

IHC

The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA904948(NMT1 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200)