The NR1I2 gene encodes the nuclear receptor subfamily 1, group I, member 2 protein, also known as PPAR-gamma. This protein functions as a transcription factor that regulates gene expression in response to various ligands. NR1I2 is involved in the peroxisome proliferator-activated receptor (PPAR) signaling pathway, which plays a crucial role in lipid metabolism and inflammation. Dysregulation of NR1I2 has been linked to inflammatory bowel disease, and research into its role in this context may lead to novel therapeutic strategies. Current drug development efforts are focused on modulating NR1I2 activity for potential treatments of metabolic disorders and inflammatory conditions.
Recombinant Human Nuclear receptor subfamily 1 group I member 2 (NR1I2) (CSB-EP016048HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP016048HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) NR1I2.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP016048HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) NR1I2.
NR1I2 Antibody (CSB-PA016048ESR1HU)
Validated Data
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA016048ESR1HU at dilution of 1:100
The following NR1I2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
NR1I2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA016048GA01HU | NR1I2 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA016048ESR1HU | NR1I2 Antibody | Human | ELISA, IHC |
CSB-PA070162 | NR1I2 Antibody | Human | WB, ELISA |
NR1I2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP016048HU CSB-BP016048HU CSB-MP016048HU CSB-EP016048HU-B |
Recombinant Human Nuclear receptor subfamily 1 group I member 2 (NR1I2) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP016048HU | Recombinant Human Nuclear receptor subfamily 1 group I member 2 (NR1I2) | E.coli |
NR1I2 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP016048MO CSB-EP016048MO CSB-BP016048MO CSB-MP016048MO CSB-EP016048MO-B |
Recombinant Mouse Nuclear receptor subfamily 1 group I member 2 (Nr1i2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NR1I2 Proteins for Macaca mulatta (Rhesus macaque)
Code | Product Name | Source |
---|---|---|
CSB-YP848312MOW CSB-EP848312MOW CSB-BP848312MOW CSB-MP848312MOW CSB-EP848312MOW-B |
Recombinant Macaca mulatta Nuclear receptor subfamily 1 group I member 2 (NR1I2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NR1I2 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP889932RA CSB-EP889932RA CSB-BP889932RA CSB-MP889932RA CSB-EP889932RA-B |
Recombinant Rat Nuclear receptor subfamily 1 group I member 2 (Nr1i2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |