NR2F2 encodes the nuclear receptor subfamily 2 group F member 2 protein, also commonly known as COUP - TFII. This protein acts as a transcription factor. It binds to specific DNA sequences and regulates gene expression. It is involved in the Wnt and Notch signaling pathways, which are crucial for cell fate determination and tissue development.
Dysregulation of NR2F2 is associated with various diseases, including congenital heart defects and certain types of cancer. In drug development, researchers are exploring small - molecule inhibitors targeting NR2F2 to interfere with its function in disease - related pathways, aiming to develop new therapies for these conditions.
Recombinant Human Nuclear receptor subfamily 2 group F member 6 (NR2F6) (CSB-EP016058HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP016058HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) NR2F6.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP016058HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) NR2F6.
NR2F6 Antibody (CSB-PA016058LA01HU)
Validated Data
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA016058LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA016058LA01HU at dilution of 1:100
The following NR2F2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
NR2F2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA244735 | NR2F6 Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA002242 | NR2F6 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA016058LA01HU | NR2F6 Antibody | Human | ELISA, IHC |
CSB-PA016058LB01HU | NR2F6 Antibody, HRP conjugated | Human | ELISA |
CSB-PA016058LC01HU | NR2F6 Antibody, FITC conjugated | Human |
NR2F2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP016058HU CSB-BP016058HU CSB-EP016058HU-B |
Recombinant Human Nuclear receptor subfamily 2 group F member 6 (NR2F6) | Yeast Baculovirus In Vivo Biotinylation in E.coli |
CSB-MP016058HU | Recombinant Human Nuclear receptor subfamily 2 group F member 6 (NR2F6) | Mammalian cell |
CSB-EP016058HU | Recombinant Human Nuclear receptor subfamily 2 group F member 6 (NR2F6) | E.coli |
CSB-EP016058HUe1 | Recombinant Human Nuclear receptor subfamily 2 group F member 6 (NR2F6) | E.coli |
CSB-EP016058HUa0 | Recombinant Human Nuclear receptor subfamily 2 group F member 6 (NR2F6) | E.coli |