NTMT1

NTMT1, identified as protein α-N-terminal methyltransferase 1, is a methyltransferase enzyme that plays a critical role in the methylation of protein N-termini, a process implicated in the initiation and progression of cancer. This enzyme regulates cellular processes such as mitosis, chromatin interaction, and DNA repair, thereby maintaining genomic stability. NTMT1's overexpression has been observed across various cancer types, including melanoma, colorectal cancer, and cervical cancer, with its levels correlating to tumor prognosis and advancement, underscoring its significance in tumor development.