PCGF2 Research Reagents

Polycomb group RING finger protein 2 is a protein in humans that is encoded by PCGF2 gene. Transcriptional repressor. Binds specifically to the DNA sequence 5'-GACTNGACT-3'. Has tumor suppressor activity. May play a role in control of cell proliferation and/or neural cell development. Regulates proliferation of early T progenitor cells by maintaining expression of HES1. Also plays a role in antero-posterior specification of the axial skeleton and negative regulation of the self-renewal activity of hematopoietic stem cells (By similarity). Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility

The following PCGF2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

PCGF2 Antibodies

PCGF2 Antibodies for Homo sapiens (Human)

PCGF2 Proteins

PCGF2 Proteins for Mus musculus (Mouse)

PCGF2 Proteins for Homo sapiens (Human)

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