Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform is a protein in humans that is encoded by PIK3CD gene. Phosphoinositide-3-kinase (PI3K) that phosphorylates PftdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Mediates immune responses. Plays a role in B-cell development, proliferation, migration, and function. Required for B-cell receptor (BCR) signaling. Mediates B-cell proliferation response to anti-IgM, anti-CD40 and IL4 stimulation.
The following PIK3CD reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
PIK3CD Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
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CSB-PA006089 | PIK3CD Antibody | Human,Mouse | WB, ELISA |
CSB-PA597940 | PIK3CD Antibody | Human,Mouse | ELISA,IHC |
CSB-PA193486 | PIK3CD Antibody | Human,Mouse | ELISA,IHC |
PIK3CD Proteins for Homo sapiens (Human)
Code | Product Name | Source |
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CSB-YP018000HU CSB-EP018000HU CSB-BP018000HU CSB-MP018000HU CSB-EP018000HU-B |
Recombinant Human Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PIK3CD), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PIK3CD Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP018000MO CSB-EP018000MO CSB-BP018000MO CSB-MP018000MO CSB-EP018000MO-B |
Recombinant Mouse Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Pik3cd), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |