PNMA1

PNMA1, also known as Paraneoplastic Ma antigen 1, is a protein - coding gene. This protein is commonly referred to as Ma1. Its action mechanism mainly involves regulating certain intracellular signal transductions. It participates in the MAPK signaling pathway, which is crucial for cell growth, differentiation, and apoptosis.
Defects in PNMA1 are linked to paraneoplastic neurological syndromes, where the immune system attacks the nervous system. Regarding drug development, research is still in the early stages. Scientists are exploring potential therapies targeting this protein to manage related diseases, aiming to develop more effective treatment strategies.