PRDX6, also known as Peroxiredoxin-6, is a multifunctional enzyme with antioxidant and pro-oxidant properties. It plays a crucial role in redox homeostasis by scavenging reactive oxygen species (ROS) and maintaining cellular integrity. PRDX6 is involved in various signaling pathways, including the JAK2/STAT3 pathway, which is linked to oncogenesis and progression. The protein is associated with several diseases, such as asthma, non-small-cell lung cancer (NSCLC), and acute lung injury (ALI). Research on PRDX6 has led to potential therapeutic targets for drug development, focusing on modulating its activity to treat oxidative stress-related disorders.
PRDX6 Antibody (CSB-PA018659LA01HU)
Validated Data
Western Blot
Positive WB detected in: A549 whole cell lysate, Hela whole cell lysate, SH-SY5Y whole cell lysate
All lanes: PRDX6 antibody at 4μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 26 kDa
Observed band size: 26 kDa
Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA018659LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human glioma using CSB-PA018659LA01HU at dilution of 1:100
Immunofluorescent analysis of Hela cells using CSB-PA018659LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunoprecipitating PRDX6 in Hela whole cell lysate
Lane 1: Rabbit control IgG (1μg) instead of CSB-PA018659LA01HU in Hela whole cell lysate.
For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
Lane 2: CSB-PA018659LA01HU (8μg) + Hela whole cell lysate (500μg)
Lane 3: Hela whole cell lysate (10μg)
Human Peroxiredoxin-6(PRDX6) ELISA kit (CSB-EL018659HU)
Validated Data
Code: CSB-EL018659HU
Size: 96T,5×96T,10×96T
Sensitivity: 3.12 pg/mL
Detection Range: 12.5 pg/mL-800 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following PRDX6 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
PRDX6 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA018659GA01HU | PRDX6 Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA968257 | PRDX6 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA596780 | PRDX6 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA018659LA01HU | PRDX6 Antibody | Human | ELISA, WB, IHC, IF, IP |
CSB-PA018659LB01HU | PRDX6 Antibody, HRP conjugated | Human | ELISA |
CSB-PA018659LC01HU | PRDX6 Antibody, FITC conjugated | Human | |
CSB-PA018659LD01HU | PRDX6 Antibody, Biotin conjugated | Human | ELISA |
PRDX6 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP018659HU CSB-EP018659HU CSB-BP018659HU CSB-MP018659HU CSB-EP018659HU-B |
Recombinant Human Peroxiredoxin-6 (PRDX6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRDX6 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL018659HU | Human Peroxiredoxin-6(PRDX6) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 3.12 pg/mL |