PRMT6, a member of the protein arginine methyltransferase family, is a nuclear enzyme derived from human genetic material. This crucial epigenetic regulator orchestrates the methylation of arginine residues, particularly through asymmetric dimethylation, thereby influencing gene expression and transcriptional regulation. PRMT6 plays a significant role in various biological processes, including cellular metabolism and DNA damage repair. Additionally, it is involved in both physiological and pathological events, such as cancer development and immune response dynamics. When PRMT6 activity deviates from normal levels, it can lead to a range of diseases, making it a key focus in the exploration of disease mechanisms and the development of innovative therapeutic strategies.
PRMT6 Antibody (CSB-PA856972LA01HU)
Validated Data
Western blot
All lanes: PRMT6 antibody at 0.4μg/ml
Lane 1: 293T whole cell lysate
Lane 2: MCF-7 whole cell lysate
Lane 3: A431 whole cell lysate
Lane 4: K562 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 42, 33 kDa
Observed band size: 42 kDa
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA856972LA01HU at dilution of 1:100
Immunofluorescent analysis of Hela cells using CSB-PA856972LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
The following PRMT6 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
PRMT6 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA018735GA01HU | PRMT6 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA856972LA01HU | PRMT6 Antibody | Human | ELISA, WB, IHC, IF |
CSB-PA856972HA01HU | PRMT6 Antibody | Human | ELISA, IHC, IF |
PRMT6 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP856972HU CSB-EP856972HU CSB-BP856972HU CSB-MP856972HU CSB-EP856972HU-B |
Recombinant Human Protein arginine N-methyltransferase 6 (PRMT6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |