PROK1

Protein encoded by the PROK1 gene is Prokineticin 1, also known as EG-VEGF or endocrine gland-derived vascular endothelial growth factor. It exerts its effects mainly through binding to prokineticin receptors (PKR1 and PKR2), triggering downstream signaling pathways such as the MAPK and PI3K/AKT pathways.
Prokineticin 1 is involved in various physiological processes including angiogenesis, neurogenesis, and regulation of the reproductive and immune systems. Abnormalities in PROK1 have been linked to several diseases, like some types of cancer and reproductive disorders. Some drugs targeting its signaling pathways are under research for potential therapeutic applications.

Popular Product:

PROK1 Antibody (CSB-PA018746LA01HU)

Validated Data

IHC image of CSB-PA018746LA01HU diluted at 1:200 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

IHC image of CSB-PA018746LA01HU diluted at 1:200 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Human prokineticin 1(PROK1/EG-VEGF) ELISA kit (CSB-E04532h)

Validated Data

Code: CSB-E04532h

Size: 96T,5×96T,10×96T

Sensitivity: 0.078 ng/mL

Detection Range: 0.312 ng/mL-20 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following PROK1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

PROK1 Antibodies

PROK1 Proteins

PROK1 ELISA Kits

PROK1 Antibodies

PROK1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA018746LA01HU	PROK1 Antibody	Human	ELISA, IHC
CSB-PA018746LB01HU	PROK1 Antibody, HRP conjugated	Human	ELISA
CSB-PA018746LC01HU	PROK1 Antibody, FITC conjugated	Human
CSB-PA018746LD01HU	PROK1 Antibody, Biotin conjugated	Human	ELISA

PROK1 Proteins

PROK1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP018746HU CSB-EP018746HU CSB-BP018746HU CSB-MP018746HU CSB-EP018746HU-B	Recombinant Human Prokineticin-1 (PROK1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP002671HU	Recombinant Human Prokineticin-1 protein (PROK1) (Active)	E.coli

PROK1 ELISA Kit

PROK1 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E04532h	Human prokineticin 1(PROK1/EG-VEGF) ELISA kit	serum	0.078 ng/mL

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