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Double-strand-break repair protein rad21 homolog is a protein in humans that is encoded by RAD21 gene. Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis.
The following RAD21 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
RAD21 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA590651 | RAD21 Antibody |
Human,Mouse | ELISA,WB |
| CSB-PA040139 | RAD21 Antibody |
Human,Mouse | WB, IHC, IF, ELISA |
| CSB-PA019257XA01HU | RAD21 Antibody |
Homo sapiens (Human) | ELISA, WB (ensure identification of antigen) |
RAD21 Antibodies for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA341177XA01SXV | rad21 Antibody |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) | ELISA, WB (ensure identification of antigen) |
RAD21 Antibodies for Mus musculus (Mouse)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA713978XA01MO | Rad21 Antibody |
Mus musculus (Mouse) | ELISA, WB (ensure identification of antigen) |
RAD21 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP019257HU CSB-EP019257HU CSB-BP019257HU CSB-MP019257HU CSB-EP019257HU-B |
Recombinant Human Double-strand-break repair protein rad21 homolog (RAD21) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RAD21 Proteins for Xenopus laevis (African clawed frog)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP019257XBE CSB-EP019257XBE CSB-BP019257XBE CSB-MP019257XBE CSB-EP019257XBE-B |
Recombinant Xenopus laevis Double-strand-break repair protein rad21 homolog (rad21), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RAD21 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP341177SXV CSB-EP341177SXV CSB-BP341177SXV CSB-MP341177SXV CSB-EP341177SXV-B |
Recombinant Schizosaccharomyces pombe Cohesin subunit rad21 (rad21), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RAD21 Proteins for Bos taurus (Bovine)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP668778BO CSB-EP668778BO CSB-BP668778BO CSB-MP668778BO CSB-EP668778BO-B |
Recombinant Bovine Double-strand-break repair protein rad21 homolog (RAD21), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RAD21 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP713978MO CSB-EP713978MO CSB-BP713978MO CSB-MP713978MO CSB-EP713978MO-B |
Recombinant Mouse Double-strand-break repair protein rad21 homolog (Rad21) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
