Replication protein A 32 kDa subunit is a protein in humans that is encoded by RPA2 gene. As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. Through recruitment of ATRIP activates the ATR kinase a master regulator of the DNA damage response. It is required for the recruitment of the DNA double-strand break repair factors RAD51 and RAD52 to chromatin in response to DNA damage.
The following RPA2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
RPA2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA01555A0Rb | RPA2 Antibody |
Human | ELISA, WB, IHC, IF, IP |
CSB-PA020089GA01HU | RPA2 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA573246 | Phospho-RPA2 (Thr21) Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA086465 | RPA2 (Ab-21) Antibody |
Human,Mouse | ELISA,WB,IHC |
CSB-PA000656 | Phospho-RPA2 (S33) Antibody |
Human,Mouse,Rat | WB, ELISA |
CSB-PA040232 | Phospho-RPA2 (T21) Antibody |
Human,Mouse | WB, IHC, ELISA |
CSB-PA040233 | RPA2 Antibody |
Human,Mouse | WB, IHC, IF, ELISA |
CSB-PA967113 | RPA2 Antibody |
Human | ELISA,WB,IHC |
CSB-PA249582 | RPA2 Antibody |
Human | ELISA,WB,IHC |
CSB-RA020089A21phHU | Phospho-RPA2 (T21) Recombinant Monoclonal Antibody |
Human | ELISA, IF |
RPA2 Antibodies for Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA758781XA01DOT | RPA2 Antibody |
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) | ELISA, WB (ensure identification of antigen) |
RPA2 Antibodies for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA865279XA01SXV | rpa2 Antibody |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) | ELISA, WB (ensure identification of antigen) |
RPA2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP020089HU CSB-EP020089HU CSB-BP020089HU CSB-MP020089HU CSB-EP020089HU-B |
Recombinant Human Replication protein A 32 kDa subunit (RPA2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP020089HU1 | Recombinant Human Replication protein A 32 kDa subunit (RPA2), partial |
E.coli |
RPA2 Proteins for Euplotes octocarinatus
Code | Product Name | Source |
---|---|---|
CSB-YP018323EPO CSB-EP018323EPO CSB-BP018323EPO CSB-MP018323EPO CSB-EP018323EPO-B |
Recombinant DNA-directed RNA polymerase I subunit RPA2 (RPA2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RPA2 Proteins for Crithidia fasciculata
Code | Product Name | Source |
---|---|---|
CSB-YP632564DXW CSB-EP632564DXW CSB-BP632564DXW CSB-MP632564DXW CSB-EP632564DXW-B |
Recombinant Replication protein A 28 kDa subunit (RPA2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RPA2 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Code | Product Name | Source |
---|---|---|
CSB-YP712965PYX CSB-EP712965PYX CSB-BP712965PYX CSB-MP712965PYX CSB-EP712965PYX-B |
Recombinant Pongo abelii Replication protein A 32 kDa subunit (RPA2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RPA2 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP730779MO CSB-EP730779MO CSB-BP730779MO CSB-MP730779MO CSB-EP730779MO-B |
Recombinant Mouse Replication protein A 32 kDa subunit (Rpa2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RPA2 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP733946RA CSB-EP733946RA CSB-BP733946RA CSB-MP733946RA CSB-EP733946RA-B |
Recombinant Rat Replication protein A 32 kDa subunit (Rpa2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RPA2 Proteins for Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Code | Product Name | Source |
---|---|---|
CSB-YP758781DOT CSB-EP758781DOT CSB-BP758781DOT CSB-MP758781DOT CSB-EP758781DOT-B |
Recombinant Ashbya gossypii DNA-directed RNA polymerase I subunit RPA2 (RPA2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RPA2 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Code | Product Name | Source |
---|---|---|
CSB-YP865279SXV CSB-EP865279SXV CSB-BP865279SXV CSB-MP865279SXV CSB-EP865279SXV-B |
Recombinant Schizosaccharomyces pombe Probable DNA-directed RNA polymerase I subunit RPA2 (rpa2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |