Sentrin-specific protease 2 is a protein in humans that is encoded by SENP2 gene. Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1. Plays a dynamic role in adipogenesis by desumoylating and promoting the stabilization of CEBPB.
The following SENP2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
SENP2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA040186 | SENP2 Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA727078 | SENP2 Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-PA692718 | SENP2 Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-PA888026LA01HU | SENP2 Antibody |
Human, Mouse | ELISA, WB, IHC, IF |
CSB-PA888026LB01HU | SENP2 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA888026LC01HU | SENP2 Antibody, FITC conjugated |
Human | |
CSB-PA888026LD01HU | SENP2 Antibody, Biotin conjugated |
Human | ELISA |
SENP2 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Code | Product Name | Source |
---|---|---|
CSB-YP722320PYX CSB-EP722320PYX CSB-BP722320PYX CSB-MP722320PYX CSB-EP722320PYX-B |
Recombinant Pongo abelii Sentrin-specific protease 2 (SENP2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SENP2 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP856342MO CSB-EP856342MO CSB-BP856342MO CSB-MP856342MO CSB-EP856342MO-B |
Recombinant Mouse Sentrin-specific protease 2 (Senp2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SENP2 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP866815RA CSB-EP866815RA CSB-BP866815RA CSB-MP866815RA CSB-EP866815RA-B |
Recombinant Rat Sentrin-specific protease 2 (Senp2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SENP2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP888026HU CSB-EP888026HU CSB-BP888026HU CSB-MP888026HU CSB-EP888026HU-B |
Recombinant Human Sentrin-specific protease 2 (SENP2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |