SLC24A4 encodes the sodium/calcium/potassium exchanger 4 (NCKX4), a plasma membrane protein belonging to the solute carrier 24 family. It mediates electroneutral exchange of 4 Na⁺ for 1 Ca²⁺ and 1 K⁺, regulating intracellular calcium homeostasis in various tissues, including retinal photoreceptors and neurons.
NCKX4 dysfunction is linked to retinal degenerative diseases and neuronal excitotoxicity. Its role in calcium signaling pathways makes it a potential target for neuroprotective drug development, though specific therapeutic agents are currently in preclinical investigation.
SLC24A4 Antibody (CSB-PA129178)
Validated Data
Western blot analysis of extracts from RAW264.7 cells, using SLC24A4 antibody.
The following SLC24A4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
SLC24A4 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA021472GA01HU | SLC24A4 Antibody | Human,Mouse | ELISA,WB |
CSB-PA129178 | SLC24A4 Antibody | Human,Mouse | ELISA,WB |
CSB-PA006991 | SLC24A4 Antibody | Human,Mouse,Rat | WB, ELISA |
CSB-PA939107 | SLC24A4 Antibody | Human | ELISA,IHC |
SLC24A4 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP850879HU CSB-EP850879HU CSB-BP850879HU CSB-MP850879HU CSB-EP850879HU-B |
Recombinant Human Sodium/potassium/calcium exchanger 4 (SLC24A4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |