Zinc finger protein SNAI1 is a protein in humans that is encoded by SNAI1 gene. Involved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate (TPA)-induced up-regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself.
The following SNAI1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
SNAI1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA021867GA01HU | SNAI1 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA299638 | Phospho-SNAI1 (Ser246) Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA162021 | SNAI1 Antibody |
Human,Mouse | ELISA,WB,IHC |
CSB-PA298000 | Phospho-SNAI1 (Ser246) Antibody |
Human,Mouse | ELISA,WB,IF |
CSB-PA041790 | SNAI1 (Ab-246) Antibody |
Human,Mouse | ELISA,WB |
CSB-PA004123 | SNAI1 Antibody |
Human,Mouse,Monkey | WB, IHC, IF, ELISA |
CSB-PA050110 | Phospho-SNAI1 (S246) Antibody |
Human,Mouse,Monkey | WB, IHC, IF, ELISA |
CSB-PA991705 | SNAI1 Antibody |
Human,Mouse | ELISA,WB,IHC |
CSB-PA021867LA01HU | SNAI1 Antibody |
Human | ELISA, IHC |
CSB-PA021867LD01HU | SNAI1 Antibody, Biotin conjugated |
Human | ELISA |
CSB-PA021867LB01HU | SNAI1 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA021867LC01HU | SNAI1 Antibody, FITC conjugated |
Human |
SNAI1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP021867HU CSB-EP021867HU CSB-BP021867HU CSB-MP021867HU CSB-EP021867HU-B |
Recombinant Human Zinc finger protein SNAI1 (SNAI1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SNAI1 Proteins for Xenopus laevis (African clawed frog)
Code | Product Name | Source |
---|---|---|
CSB-YP322525XBE CSB-EP322525XBE CSB-BP322525XBE CSB-MP322525XBE CSB-EP322525XBE-B |
Recombinant Xenopus laevis Protein snail homolog Sna (snai1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |