Suppressor of cytokine signaling 7 is a protein in humans that is encoded by SOCS7 gene. Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
The following SOCS7 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
SOCS7 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA050626 | SOCS7 Antibody |
Human,Mouse | ELISA,IHC |
CSB-PA062278 | SOCS7 Antibody |
Human,Mouse | ELISA,IHC |
CSB-PA022396LA01HU | SOCS7 Antibody |
Human, Rat | ELISA, WB, IF |
CSB-PA022396LB01HU | SOCS7 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA022396LC01HU | SOCS7 Antibody, FITC conjugated |
Human | |
CSB-PA022396LD01HU | SOCS7 Antibody, Biotin conjugated |
Human | ELISA |
SOCS7 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP022396HU CSB-EP022396HU CSB-BP022396HU CSB-MP022396HU CSB-EP022396HU-B |
Recombinant Human Suppressor of cytokine signaling 7 (SOCS7) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SOCS7 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP022396MO CSB-EP022396MO CSB-BP022396MO CSB-MP022396MO CSB-EP022396MO-B |
Recombinant Mouse Suppressor of cytokine signaling 7 (Socs7) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |