STAT5A, a member of the STAT protein family and a transcription factor encoded by the STAT5A gene, is expressed across various cell types. Upon phosphorylation by JAK kinase in response to cytokines or growth factors, STAT5A forms dimers that translocate to the nucleus to regulate gene expression. It is involved in the regulation of cell proliferation, differentiation, apoptosis, lactation, and immune responses. STAT5A dysfunction is linked to diseases such as cancer, immunodeficiency, and developmental disorders, positioning it as a potential target for drug development and treatment.
Phospho-STAT5A (Y694) Recombinant Monoclonal Antibody (CSB-RA022814A694phHU)
Validated Data
Western Blot
Positive WB detected in HepG2 whole cell lysate(treated with EGF or not)
All lanes Phospho-STAT5A antibody at 1.025μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 90 KDa
Observed band size: 90 KDa
IHC image of CSB-RA022814A694phHU diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
The following STAT5A reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
STAT5A Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA022814GA01HU | STAT5A Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA877372 | Phospho-STAT5A (Tyr694) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA137661 | Phospho-STAT5A (Ser780) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA094290 | STAT5A (Ab-694) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA103883 | STAT5A (Ab-780) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA052847 | STAT5A Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA004179 | STAT5A Antibody | Human,Mouse,Rat | WB, IF, ELISA |
CSB-PA004180 | STAT5A Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA050167 | Phospho-STAT5A (S780) Antibody | Human,Mouse,Rat | WB, IHC, IP, ELISA |
CSB-PA080243 | STAT5A Antibody | Human | WB, IHC |
CSB-PA080262 | STAT5A Antibody | Rat,Mouse | WB, IHC |
CSB-PA554957 | STAT5A Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-RA022814A694phHU | Phospho-STAT5A (Y694) Recombinant Monoclonal Antibody | Human | ELISA, WB, IHC |
STAT5A Antibodies for Mus musculus (Mouse)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA952305 | Phospho-Stat5a/Stat5b (Ser725/730) Antibody | Human,Mouse,Rat | ELISA,WB |
STAT5A Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP022814HU CSB-EP022814HU CSB-BP022814HU CSB-MP022814HU CSB-EP022814HU-B |
Recombinant Human Signal transducer and activator of transcription 5A (STAT5A) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
STAT5A Proteins for Ovis aries (Sheep)
Code | Product Name | Source |
---|---|---|
CSB-YP022814SH CSB-EP022814SH CSB-BP022814SH CSB-MP022814SH CSB-EP022814SH-B |
Recombinant Sheep Signal transducer and activator of transcription 5A (STAT5A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
STAT5A Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP022814MO CSB-EP022814MO CSB-BP022814MO CSB-MP022814MO CSB-EP022814MO-B |
Recombinant Mouse Signal transducer and activator of transcription 5A (Stat5a) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
STAT5A Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP022814RA CSB-EP022814RA CSB-BP022814RA CSB-MP022814RA CSB-EP022814RA-B |
Recombinant Rat Signal transducer and activator of transcription 5A (Stat5a) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
STAT5A Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP022814BO CSB-EP022814BO CSB-BP022814BO CSB-MP022814BO CSB-EP022814BO-B |
Recombinant Bovine Signal transducer and activator of transcription 5A (STAT5A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
STAT5A Proteins for Sus scrofa (Pig)
Code | Product Name | Source |
---|---|---|
CSB-YP022814PI CSB-EP022814PI CSB-BP022814PI CSB-MP022814PI CSB-EP022814PI-B |
Recombinant Pig Signal transducer and activator of transcription 5A (STAT5A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |