Thrombospondin-4is a protein in humans that is encoded by THBS4 gene. Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and is involved in various processes including cellular proliferation, migration, adhesion and attachment, inflammatory response to CNS injury, regulation of vascular inflammation and adaptive responses of the heart to pressure overload and in myocardial function and remodeling. Binds to structural extracellular matrix (ECM) proteins and modulates the ECM in response to tissue damage, contributing to cardioprotective and adaptive ECM remodeling. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors and protects myocardium from pressure overload. May contribute to spinal presynaptic hypersensitivity and neuropathic pain states after peripheral nerve injury.
The following THBS4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
THBS4 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA050258 | THBS4 Antibody |
Human | WB, IHC, ELISA |
CSB-PA562708 | THBS4 Antibody |
Human | IHC,ELISA |
THBS4 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP023490HU CSB-EP023490HU CSB-BP023490HU CSB-MP023490HU CSB-EP023490HU-B |
Recombinant Human Thrombospondin-4 (THBS4), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
THBS4 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP023490RA CSB-EP023490RA CSB-BP023490RA CSB-MP023490RA CSB-EP023490RA-B |
Recombinant Rat Thrombospondin-4 (Thbs4), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
THBS4 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP659633BO CSB-EP659633BO CSB-BP659633BO CSB-MP659633BO CSB-EP659633BO-B |
Recombinant Bovine Thrombospondin-4 (THBS4), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
THBS4 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL023490HU | Human Thrombospondin-4(THBS4) ELISA kit |
serum, plasma | 1.95 ng/mL |