TICAM1 Research Reagents

TIR domain-containing adapter molecule 1 is a protein in humans that is encoded by TICAM1 gene. Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.

The following TICAM1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

TICAM1 Antibodies

TICAM1 Antibodies for Homo sapiens (Human)

TICAM1 Antibodies for Mus musculus (Mouse)

TICAM1 Proteins

TICAM1 Proteins for Bos taurus (Bovine)

TICAM1 Proteins for Mus musculus (Mouse)

TICAM1 Proteins for Homo sapiens (Human)

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