TNFSF13

TNFSF13, also known as APRIL, stands out as a significant member of the tumor necrosis factor superfamily, exhibiting high expression levels in immune-related tissues such as lymphoid tissue, spleen, and bone marrow. As a polypeptide, TNFSF13 plays a crucial role in humoral immunity by regulating B-cell activation and antibody production. Through interactions with receptors like BCMA and TACI, it promotes the proliferation and survival of B cells. Recombinant TNFSF13 protein, artificially produced, possesses specific biological activities and is widely used in scientific research, including SDS-PAGE analysis and other functional studies. This recombinant protein holds potential applications in immune modulation and anti-inflammatory therapy, offering new possibilities for the development of immunotherapy strategies.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human TNFSF13 protein at 2 μg/ml can bind Human TNFRSF17 protein (CSB-MP023974HU1-B). The EC₅₀ is 0.8083-0.9391 ng/mL.

Activity
Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis TNFRSF13B protein (CSB-MP6427MOV) at 2 μg/ml can bind Human TNFSF13 protein. The EC₅₀ is 11.13-18.97 ng/mL.

TNFSF13 Antibody (CSB-PA023989ESR1HU)

Validated Data

Western blot
All lanes: Tumor necrosis factor ligand superfamily member 13 antibody at 10μg/ml + Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 28, 26, 25, 37, 23 kDa
Observed band size: 28 kDa

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA023989ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA023989ESR1HU at dilution of 1:100

The following TNFSF13 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

TNFSF13 Antibodies

TNFSF13 Proteins

TNFSF13 ELISA Kits

TNFSF13 Antibodies

TNFSF13 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA023989GA01HU	TNFSF13 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA023989ESR1HU	TNFSF13 Antibody	Human	ELISA, WB, IHC
CSB-PA023989ESR2HU	TNFSF13 Antibody	Human	ELISA, IHC
CSB-PA244663	TNFSF13 Antibody	Human,Mouse,Rat	ELISA,WB,IHC,IF
CSB-PA000909	TNFSF13 Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA877550	TNFSF13 Antibody	Human,Mouse	ELISA,IHC
CSB-PA935662	TNFSF13 Antibody	Human,Mouse	ELISA,IHC
CSB-PA599200	TNFSF13 Antibody	Human,Mouse	ELISA,IHC
CSB-PA587516	TNFSF13 Antibody	Human,Mouse	ELISA,IHC

TNFSF13 Proteins

TNFSF13 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP023989HU CSB-EP023989HU CSB-BP023989HU CSB-MP023989HU CSB-EP023989HU-B	Recombinant Human Tumor necrosis factor ligand superfamily member 13 (TNFSF13)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNFSF13 ELISA Kit

TNFSF13 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E15012h	Human a proliferation inducing ligand(APRIL)ELISA Kit	serum, plasma, urine	0.195 ng/mL

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TNFSF13

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