TXNIP Research Reagents

Thioredoxin-interacting protein is a protein in humans that is encoded by TXNIP gene. May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).

The following TXNIP reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

TXNIP Antibodies

TXNIP Antibodies for Mus musculus (Mouse)

TXNIP Antibodies for Homo sapiens (Human)

TXNIP Proteins

TXNIP Proteins for Sus scrofa (Pig)

TXNIP Proteins for Rattus norvegicus (Rat)

TXNIP Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

TXNIP Proteins for Mus musculus (Mouse)

TXNIP Proteins for Homo sapiens (Human)

TXNIP ELISA Kit

TXNIP ELISA Kit for Homo sapiens (Human)

TXNIP ELISA Kit for Mus musculus (Mouse)

TXNIP ELISA Kit for Rattus norvegicus (Rat)

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