VASH1

VASH1, also known as Vasohibin 1, is a protein coding gene that plays a crucial role in regulating angiogenesis and lymphangiogenesis. It functions by mediating tubulin detyrosination, a post-translational modification involved in various cellular processes such as cell division. VASH1 is selectively expressed in endothelial cells and has been implicated in diseases like portal hypertension and pheochromocytoma. Its dysregulation can lead to defective lymphatic vessel formation and lymphangiogenesis, suggesting its potential involvement in cancer and other pathologies.
Recent studies have explored the role of VASH1 in drug development, particularly in the context of angiogenesis and lymphangiogenesis-related diseases. Research indicates that VASH1 may serve as a therapeutic target, with potential applications in the development of new drugs aimed at modulating these processes for therapeutic benefits.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

VASH1 Antibody (CSB-PA745337HA01HU)

Validated Data

IHC image of CSB-PA745337HA01HU diluted at 1:500 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

IHC image of CSB-PA745337HA01HU diluted at 1:500 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Human Vasohibin-1(VASH1) ELISA kit (CSB-EL025794HU)

Validated Data

Code: CSB-EL025794HU

Size: 96T,5×96T,10×96T

Sensitivity: 15.6 pg/mL

Detection Range: 62.5 pg/mL-4000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following VASH1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

VASH1 Antibodies

VASH1 Proteins

VASH1 ELISA Kits

VASH1 Antibodies

VASH1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA025794GA01HU	VASH1 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA745337GA01HU	VASH1 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA745337HA01HU	VASH1 Antibody	Human	ELISA, IHC
CSB-PA745337HB01HU	VASH1 Antibody, HRP conjugated	Human	ELISA
CSB-PA745337HD01HU	VASH1 Antibody, Biotin conjugated	Human	ELISA
CSB-PA149592	VASH1 Antibody	Human	ELISA,WB
CSB-PA004420	VASH1 Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA899191	VASH1 Antibody	Human,Mouse	ELISA,WB,IHC
CSB-PA562311	VASH1 Antibody	Human,Mouse	ELISA,WB,IHC

VASH1 Proteins

VASH1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP745337HU CSB-BP745337HU CSB-MP745337HU CSB-EP745337HU-B	Recombinant Human Tubulinyl-Tyr carboxypeptidase 1 (VASH1)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP745337HU	Recombinant Human Tubulinyl-Tyr carboxypeptidase 1 (VASH1)	E.coli

VASH1 ELISA Kit

VASH1 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL025794HU	Human Vasohibin-1(VASH1) ELISA kit	serum, plasma, tissue homogenates	15.6 pg/mL

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VASH1

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