WNT7B

WNT7B (Wnt family member 7B), also known as WNT-7B, is a secreted glycoprotein of the Wnt ligand family. It signals via binding to Frizzled receptors and LRP5/6 co-receptors, activating both canonical (β-catenin-dependent) and non-canonical pathways. Critical roles include embryonic lung branching, neural tube closure, and adult tissue homeostasis like lung repair and bone formation.
Dysregulated WNT7B expression links to colorectal, breast, and lung cancers, promoting tumor growth and metastasis via β-catenin stabilization. It also drives myofibroblast differentiation in idiopathic pulmonary fibrosis. Preclinical studies explore targeted therapies—neutralizing antibodies or small molecules blocking receptor interactions—for cancer and fibrotic disorders.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

WNT7B Antibody (CSB-PA026142ESR1HU)

Validated Data

Western blot
All lanes: WNT7B antibody at 2.41μg/ml + Mouse small intestine tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 39 kDa
Observed band size: 39 kDa

Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA026142ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA026142ESR1HU at dilution of 1:100

Western Blot
Positive WB detected in: A549 whole cell lysate, HepG2 whole cell lysate, PC-3 whole cell lysate
All lanes: WNT7B antibody at 2.4μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 40 kDa
Observed band size: 47 kDa

Human Protein Wnt-7b(WNT7B) ELISA kit (CSB-EL026142HU)

Validated Data

Code: CSB-EL026142HU

Size: 96T,5×96T,10×96T

Sensitivity: 0.039 ng/mL

Detection Range: 0.156 ng/mL-10 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following WNT7B reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

WNT7B Antibodies

WNT7B Proteins

WNT7B ELISA Kits

WNT7B Antibodies

WNT7B Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA026142ESR1HU	WNT7B Antibody	Human, Mouse	ELISA, WB, IHC
CSB-PA026142ESR2HU	WNT7B Antibody	Human	ELISA, WB, IHC

WNT7B Antibodies for Mus musculus (Mouse)

Code	Product Name	Species Reactivity	Application
CSB-PA026142ZA01MO	Wnt7b Antibody	Mus musculus	ELISA, WB (ensure identification of antigen)

WNT7B Proteins

WNT7B Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-BP026142MO CSB-MP026142MO CSB-EP026142MO-B	Recombinant Mouse Protein Wnt-7b (Wnt7b)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP026142MO	Recombinant Mouse Protein Wnt-7b (Wnt7b)	E.coli

WNT7B Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP026142HU CSB-MP026142HU CSB-EP026142HU-B	Recombinant Human Protein Wnt-7b (WNT7B)	Yeast Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP026142HU	Recombinant Human Protein Wnt-7b (Wnt7B)	E.coli
CSB-BP026142HU	Recombinant Human Protein Wnt-7b (WNT7B)	Baculovirus

WNT7B Proteins for Meleagris gallopavo (Wild turkey)

Code	Product Name	Source
CSB-YP026142MQV CSB-EP026142MQV CSB-BP026142MQV CSB-MP026142MQV CSB-EP026142MQV-B	Recombinant Meleagris gallopavo Protein Wnt-7b (WNT7B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT7B Proteins for Xenopus laevis (African clawed frog)

Code	Product Name	Source
CSB-YP026142XBE CSB-EP026142XBE CSB-BP026142XBE CSB-MP026142XBE CSB-EP026142XBE-B	Recombinant Xenopus laevis Protein Wnt-7b (wnt7b)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT7B Proteins for Anser caerulescens (Snow goose) (Chen caerulescens)

Code	Product Name	Source
CSB-YP026142AKY CSB-EP026142AKY CSB-BP026142AKY CSB-MP026142AKY CSB-EP026142AKY-B	Recombinant Anser caerulescens Protein Wnt-7b (WNT7B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT7B Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-YP664675CH CSB-EP664675CH CSB-BP664675CH CSB-MP664675CH CSB-EP664675CH-B	Recombinant Chicken Protein Wnt-7b (WNT7B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

WNT7B ELISA Kit

WNT7B ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL026142HU	Human Protein Wnt-7b(WNT7B) ELISA kit	serum, plasma,tissue homogenates	0.039 ng/mL

WNT7B ELISA Kit for Mus musculus (Mouse)

Code	Product Name	Sample Types	Sensitivity
CSB-EL026142MO	Mouse Protein Wnt-7b(WNT7B) ELISA kit	serum, plasma, tissue homogenates	0.078 ng/mL

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