ZG16B

It has been noted that ZG16B is a mammalian lectin containing a β-prism fold structure, which contributes to the ability to regulate cell adhesion, metastasis, apoptosis, angiogenesis, and cell-cell interactions to recognize pathogens (Figure 1). ZG16B is located at the human chromosome 16p13.3 locus, a 721 bp cDNA sequence, and has a 196 amino acid. The open reading frame region of ZG16B contains a nucleic acid structure similar to that of human salivary proteins. ZG16B was first found to be highly expressed in pancreatic cancer and played an important oncogenic role, which led to its identification as a pancreatic adenocarcinoma upregulated factor (PAUF). In pancreatic adenocarcinoma, ZG16B is activated by CXCR4, TPL2, β-catenin, TPL2/MEK/ERK, FAK/Scr, and other signaling pathways, which promotes pancreatic cancer angiogenesis

More Interesting read related ZG16B：ZG16B: A New Tumor Biomarker Offer Important Insights for Drug Development in Pancreatic Cancer!

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Recombinant Human Zymogen granule protein 16 homolog B(ZG16B) (Active) (CSB-MP836195HU)

Validated Data

High Purity Validated by SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Excellent Bioactivity Validated by Functional ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ZG16B at 2 μg/ml can bind Anti-ZG16B recombinant antibody (CSB-RA836195MA1HU), the EC₅₀ is 24.13-46.04 ng/mL.

Recombinant Macaca fascicularis Jacalin-type lectin domain-containing protein (Active) CSB-MP4727MOV

Validated Data

High Purity Validated by SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Excellent Bioactivity Validated by Functional ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis ZG16B at 2μg/mL can bind Anti-ZG16B recombinant antibody (CSB-RA836195MA1HU)， the EC₅₀ is 20.15-28.98 ng/mL.