ADIPOR2 stands for Adiponectin Receptor 2. It is also known as PAQR2. This protein plays a crucial role in mediating the metabolic effects of adiponectin, an adipokine involved in energy homeostasis and insulin sensitivity. It activates multiple signaling pathways, such as AMP - activated protein kinase (AMPK) and peroxisome proliferator - activated receptor - alpha (PPAR - alpha) pathways.
Dysregulation of ADIPOR2 is associated with various diseases including type 2 diabetes, obesity, and cardiovascular diseases. In drug development, targeting ADIPOR2 has emerged as a potential strategy. Some small - molecule agonists are under pre - clinical investigation, aiming to enhance its function and improve metabolic disorders.
ADIPOR2 Antibody (CSB-PA011355)
Validated Data
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA011355(ADIPOR2 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA011355(ADIPOR2 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200)
The following ADIPOR2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
ADIPOR2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA001368GA01HU | ADIPOR2 Antibody | Human,Mouse,Rat | ELISA,WB,IP,IHC |
CSB-PA011355 | ADIPOR2 Antibody | Human,Mouse | ELISA,IHC |
CSB-PA141929 | ADIPOR2 Antibody | Human,Mouse | ELISA,IHC |
ADIPOR2 Antibodies for Oryza sativa subsp. japonica (Rice)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA227154XA01OFG | ADIPOR2 Antibody | Oryza sativa subsp. japonica (Rice) | ELISA, WB (ensure identification of antigen) |
ADIPOR2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF768214HU | Recombinant Human Adiponectin receptor protein 2 (ADIPOR2) | in vitro E.coli expression system |
CSB-YP768214HU1 CSB-EP768214HU1 CSB-BP768214HU1 CSB-MP768214HU1 CSB-EP768214HU1-B |
Recombinant Human Adiponectin receptor protein 2 (ADIPOR2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ADIPOR2 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF805321MO | Recombinant Mouse Adiponectin receptor protein 2 (Adipor2) | in vitro E.coli expression system |
CSB-YP805321MO1 CSB-EP805321MO1 CSB-BP805321MO1 CSB-MP805321MO1 CSB-EP805321MO1-B |
Recombinant Mouse Adiponectin receptor protein 2 (Adipor2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |