ANGPT1

Angiopoietin-1 is a protein in humans that is encoded by ANGPT1 gene. Binds and activates TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation. Plays an important role in the regulation of angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Required for normal angiogenesis and heart development during embryogenesis. After birth, activates or inhibits angiogenesis, depending on the context. Inhibits angiogenesis and promotes vascular stability in quiescent vessels, where endothelial cells have tight contacts. In quiescent vessels, ANGPT1 oligomers recruit TEK to cell-cell contacts, forming complexes with TEK molecules from adjoining cells, and this leads to preferential activation of phosphatidylinositol 3-kinase and the AKT1 signaling cascades.

ANGPT1 Antibodies

ANGPT1 Antibodies for Human

ANGPT1 Antibodies for Homo sapiens (Human)

ANGPT1 Proteins

ANGPT1 Proteins for Bos taurus (Bovine)

ANGPT1 Proteins for Mus musculus (Mouse)

ANGPT1 Proteins for Rattus norvegicus (Rat)

ANGPT1 Proteins for Homo sapiens (Human)

ANGPT1 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

ANGPT1 Proteins for Sus scrofa (Pig)

ANGPT1 cDNA for Bos taurus (Bovine)

Code Product Name Vector Accession NO.
CSB-CL001706BO ANGPT1 pUC NM_001076797.1

ANGPT1 cDNA for Mus musculus (Mouse)

Code Product Name Vector Accession NO.
CSB-CL001706MO Angpt1 pUC NM_009640.3

ANGPT1 cDNA for Homo sapiens (Human)

Code Product Name Vector Accession NO.
CSB-CL622996HU1 ANGPT1 pUC NM_001146.3
CSB-CL622996HU2 ANGPT1 pUC NM_001199859.1

ANGPT1 cDNA for Canis lupus familiaris (Dog) (Canis familiaris)

Code Product Name Vector Accession NO.
CSB-CL713940DO ANGPT1 pUC NM_001005754.2

ANGPT1 cDNA for Sus scrofa (Pig)

Code Product Name Vector Accession NO.
CSB-CL861039PI ANGPT1 pUC NM_213959.1

ANGPT1 ELISA Kit

ANGPT1 ELISA Kit for Bos taurus (Bovine)

ANGPT1 ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)

ANGPT1 ELISA Kit for Homo sapiens (Human)

ANGPT1 ELISA Kit for Mus musculus (Mouse)

ANGPT1 ELISA Kit for Sus scrofa (Pig)

ANGPT1 ELISA Kit for Rattus norvegicus (Rat)

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