Aldehyde oxidase is a protein in humans that is encoded by AOX1 gene. Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide, N-methylphthalazinium and phthalazine, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also may catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor. May play a role in adipogenesis.

AOX1 Antibodies

AOX1 Antibodies for Homo sapiens (Human)

AOX1 Antibodies for Human

AOX1 Antibodies for Oryctolagus cuniculus (Rabbit)

AOX1 Antibodies for Mus musculus (Mouse)

AOX1 Proteins

AOX1 Proteins for Oryctolagus cuniculus (Rabbit)

AOX1 Proteins for Bos taurus (Bovine)

AOX1 Proteins for Mus musculus (Mouse)

AOX1 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

AOX1 Proteins for Homo sapiens (Human)


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