BGN

The BGN gene encodes biglycan, a small leucine - rich proteoglycan (SLRP). It is also commonly known as PG - I and decorin - like proteoglycan. Biglycan plays a crucial role in maintaining the structural integrity of the extracellular matrix. It can bind to various growth factors and cytokines, modulating their activity and signaling.
In terms of signaling pathways, biglycan is involved in the TLR4 - mediated pathway, which is important for innate immunity. Aberrant expression of BGN is associated with diseases such as osteoporosis and certain types of cancer. Currently, research on drugs targeting biglycan is in the pre - clinical stage, aiming to develop therapies for related disorders.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

BGN Antibody (CSB-PA002683EA01HU)

Validated Data

Immunohistochemistry analysis of human pancreatic cancer using CSB-PA002683EA01HU at dilution of 1:100

Immunohistochemistry analysis of human placenta tissue using CSB-PA002683EA01HU at dilution of 1:100

Immunofluorescent analysis of HepG2 cells using CSB-PA002683EA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Human Biglycan(BGN) ELISA kit (CSB-EL002683HU)

Validated Data

Code: CSB-EL002683HU

Size: 96T,5×96T,10×96T

Sensitivity: 0.078 ng/mL

Detection Range: 0.312 ng/mL-20 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following BGN reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

BGN Antibodies

BGN Proteins

BGN ELISA Kits

BGN Antibodies

BGN Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA002683GA01HU	BGN Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA157570	BGN Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA203218	BGN Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA002683EA01HU	BGN Antibody	Human	ELISA, IHC, IF

BGN Antibodies for Mus musculus (Mouse)

Code	Product Name	Species Reactivity	Application
CSB-PA002683ZA01MO	Bgn Antibody	Mus musculus	ELISA, WB (ensure identification of antigen)

BGN Proteins

BGN Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP002683HU CSB-BP002683HU CSB-MP002683HU CSB-EP002683HU-B	Recombinant Human Biglycan (BGN)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP002683HU	Recombinant Human Biglycan (BGN)	E.coli

BGN Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP002683BO CSB-EP002683BO CSB-BP002683BO CSB-MP002683BO CSB-EP002683BO-B	Recombinant Bovine Biglycan (BGN)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

BGN Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP002683MO CSB-BP002683MO CSB-MP002683MO CSB-EP002683MO-B	Recombinant Mouse Biglycan (Bgn)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP002683MO	Recombinant Mouse Biglycan (Bgn)	E.coli

BGN Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Source
CSB-YP002683DO CSB-EP002683DO CSB-BP002683DO CSB-MP002683DO CSB-EP002683DO-B	Recombinant Dog Biglycan (BGN)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

BGN Proteins for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Source
CSB-YP002683RB CSB-EP002683RB CSB-BP002683RB CSB-MP002683RB CSB-EP002683RB-B	Recombinant Rabbit Biglycan (BGN)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

BGN Proteins for Ovis aries (Sheep)

Code	Product Name	Source
CSB-YP002683SH CSB-EP002683SH CSB-BP002683SH CSB-MP002683SH CSB-EP002683SH-B	Recombinant Sheep Biglycan (BGN)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

BGN Proteins for Equus caballus (Horse)

Code	Product Name	Source
CSB-YP002683HO CSB-EP002683HO CSB-BP002683HO CSB-MP002683HO CSB-EP002683HO-B	Recombinant Horse Biglycan (BGN)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

BGN Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP002683RA CSB-EP002683RA CSB-BP002683RA CSB-MP002683RA CSB-EP002683RA-B	Recombinant Rat Biglycan (Bgn)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

BGN Proteins for Xenopus laevis (African clawed frog)

Code	Product Name	Source
CSB-YP002683XBE CSB-EP002683XBE CSB-BP002683XBE CSB-MP002683XBE CSB-EP002683XBE-B	Recombinant Xenopus laevis Biglycan (bgn), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

BGN Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP002683PI CSB-EP002683PI CSB-BP002683PI CSB-MP002683PI CSB-EP002683PI-B	Recombinant Pig Biglycan (BGN)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

BGN ELISA Kit

BGN ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL002683HU	Human Biglycan(BGN) ELISA kit	serum, plasma, tissue homogenates	0.078 ng/mL

BGN ELISA Kit for Mus musculus (Mouse)

Code	Product Name	Sample Types	Sensitivity
CSB-EL002683MO	Mouse Biglycan(BGN) ELISA kit	serum, plasma, tissue homogenates	0.156 ng/mL

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BGN

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