BRCA1-associated protein is a protein in humans that is encoded by BRAP gene. Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.
The following BRAP reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
BRAP Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA773793LA01HU | BRAP Antibody |
Human, Rat, Mouse | ELISA, WB, IHC, IF |
CSB-PA773793LB01HU | BRAP Antibody, HRP conjugated |
Human | ELISA |
CSB-PA773793LC01HU | BRAP Antibody, FITC conjugated |
Human | |
CSB-PA773793LD01HU | BRAP Antibody, Biotin conjugated |
Human | ELISA |
BRAP Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP773793HU | Recombinant Human BRCA1-associated protein (BRAP) |
Yeast |
CSB-EP773793HU CSB-BP773793HU CSB-MP773793HU CSB-EP773793HU-B |
Recombinant Human BRCA1-associated protein (BRAP) |
E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BRAP Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP860396MO CSB-EP860396MO CSB-BP860396MO CSB-MP860396MO CSB-EP860396MO-B |
Recombinant Mouse BRCA1-associated protein (Brap) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |