CCN2

CCN2, also known as CTGF, is a protein expressed across a range of cell types. It is particularly influential in the heart, lungs, liver, kidneys, and in the context of solid organ transplantation. This factor is instrumental in regulating cellular processes such as proliferation, differentiation, adhesion, and angiogenesis. CCN2 is also involved in pathologies like tumor development and tissue fibrosis. CCN2 functions by binding to cell surface integrin receptors, activating signaling pathways like FAK, and thus impacting cell behavior and metabolism. It is vital for embryonic development, tissue regeneration, fibrotic responses, and the tumor microenvironment. Abnormal CCN2 expression is linked to various diseases, including fibrotic conditions, cardiovascular diseases, and cancers, making it a significant target for drug development.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CTGF Antibody (CSB-PA09429A0Rb)

Validated Data

Immunofluorescent analysis of HepG2 cells using CSB-PA09429A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA09429A0Rb at dilution of 1:100

Human connective tissue growth factor (CTGF) ELISA kit (CSB-E07875h)

Validated Data

Code: CSB-E07875h

Size: 96T,5×96T,10×96T

Sensitivity: 1.875 pg/mL

Detection Range: 3.75 pg/mL-120 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following CCN2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CCN2 Antibodies

CCN2 Proteins

CCN2 ELISA Kits

CCN2 Antibodies

CCN2 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA09429A0Rb	CTGF Antibody	Human	ELISA, IHC, IF
CSB-PA060417	CTGF Antibody	Human,Mouse,Rat	ELISA,WB,IHC

CCN2 Proteins

CCN2 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP006147HU CSB-BP006147HU CSB-MP006147HU CSB-EP006147HU-B	Recombinant Human CCN family member 2 (CCN2)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP006147HUe0	Recombinant Human CCN family member 2 (CCN2), partial	E.coli
CSB-EP006147HU1	Recombinant Human CCN family member 2 (CCN2), partial	E.coli
CSB-EP006147HU	Recombinant Human CCN family member 2 (CCN2)	E.coli

CCN2 ELISA Kit

CCN2 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E07875h	Human connective tissue growth factor (CTGF) ELISA kit	serum, plasma, tissue homogenates	1.875 pg/mL

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CCN2

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