CCNB1

Cyclin B1 (CCNB1), also known as Cyclin B, is a regulatory protein crucial for cell cycle progression, particularly during the transition from G2 phase to mitosis. It forms a complex with CDK1 (Cyclin-dependent kinase 1) to drive cell division. CCNB1 is overexpressed in various cancers, including breast, lung, and colorectal cancers, and is associated with aggressive tumor behavior, poor prognosis, and lymphovascular invasion. Research into CCNB1 as a therapeutic target has led to the development of inhibitors targeting the Cyclin B1-CDK1 complex, offering a novel approach to cancer therapy. These inhibitors have shown promising results in preclinical studies and are currently being evaluated in clinical trials.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CCNB1 Monoclonal Antibody (CSB-MA124445)

Validated Data

Immunohistochemical analysis of paraffin-embedded Human lung Tissue using Cyclin B1 Mouse mAb diluted at 1:200.

Immunohistochemical analysis of paraffin-embedded Human Tonsil Tissue using Cyclin B1 Mouse mAb diluted at 1:200.

The following CCNB1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CCNB1 Antibodies

CCNB1 Proteins

CCNB1 Antibodies

CCNB1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA004806GA01HU	CCNB1 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA059325	Phospho-CCNB1 (Ser147) Antibody	Human	ELISA,WB,IHC,IF
CSB-PA973969	CCNB1 (Ab-147) Antibody	Human	ELISA,WB,IHC,IF
CSB-PA000507	Phospho-CCNB1 (S126) Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA001863	CCNB1 Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA070175	Phospho-CCNB1 (S147) Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA070176	CCNB1 Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA080257	CCNB1 Antibody	Human,Mouse,Rat	WB, IHC
CSB-PA018543	CCNB1 Antibody	Human	ELISA,WB
CSB-PA959008	CCNB1 Antibody	Human	ELISA,IHC
CSB-MA124445	CCNB1 Monoclonal Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-MA820649	CCNB1 Monoclonal Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA004806ZA01HU	CCNB1 Antibody	Homo sapiens	ELISA, WB (ensure identification of antigen)

CCNB1 Proteins

CCNB1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP004806HU	Recombinant Human G2/mitotic-specific cyclin-B1 (CCNB1)	Yeast
CSB-MP004806HU CSB-EP004806HU-B	Recombinant Human G2/mitotic-specific cyclin-B1 (CCNB1)	Mammalian cell In Vivo Biotinylation in E.coli
CSB-BP004806HU	Recombinant Human G2/mitotic-specific cyclin-B1 (CCNB1)	Baculovirus
CSB-EP004806HU	Recombinant Human G2/mitotic-specific cyclin-B1 (CCNB1)	E.coli
CSB-EP004806HUa0	Recombinant Human G2/mitotic-specific cyclin-B1 (CCNB1)	E.coli

CCNB1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP004806MO CSB-EP004806MO CSB-BP004806MO CSB-MP004806MO CSB-EP004806MO-B	Recombinant Mouse G2/mitotic-specific cyclin-B1 (Ccnb1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CCNB1 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP004806RA CSB-EP004806RA CSB-BP004806RA CSB-MP004806RA CSB-EP004806RA-B	Recombinant Rat G2/mitotic-specific cyclin-B1 (Ccnb1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CCNB1 Proteins for Xenopus laevis (African clawed frog)

Code	Product Name	Source
CSB-YP004806XBE CSB-EP004806XBE CSB-BP004806XBE CSB-MP004806XBE CSB-EP004806XBE-B	Recombinant Xenopus laevis G2/mitotic-specific cyclin-B1 (ccnb1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CCNB1 Proteins for Mesocricetus auratus (Golden hamster)

Code	Product Name	Source
CSB-YP004806MRG CSB-EP004806MRG CSB-BP004806MRG CSB-MP004806MRG CSB-EP004806MRG-B	Recombinant Mesocricetus auratus G2/mitotic-specific cyclin-B1 (CCNB1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CCNB1 Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

Code	Product Name	Source
CSB-YP600848DXU CSB-EP600848DXU CSB-BP600848DXU CSB-MP600848DXU CSB-EP600848DXU-B	Recombinant Cricetulus griseus G2/mitotic-specific cyclin-B1 (CCNB1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CCNB1 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP636894BO CSB-EP636894BO CSB-BP636894BO CSB-MP636894BO CSB-EP636894BO-B	Recombinant Bovine G2/mitotic-specific cyclin-B1 (CCNB1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CCNB1 Proteins for Anguilla japonica (Japanese eel)

Code	Product Name	Source
CSB-YP713941BZH CSB-EP713941BZH CSB-BP713941BZH CSB-MP713941BZH CSB-EP713941BZH-B	Recombinant Anguilla japonica G2/mitotic-specific cyclin-B1 (ccnb1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CCNB1 Proteins for Carassius auratus (Goldfish)

Code	Product Name	Source
CSB-YP856358DQG CSB-EP856358DQG CSB-BP856358DQG CSB-MP856358DQG CSB-EP856358DQG-B	Recombinant Carassius auratus G2/mitotic-specific cyclin-B1 (ccnb1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CCNB1 Proteins for Oryzias latipes (Japanese rice fish) (Japanese killifish)

Code	Product Name	Source
CSB-YP878016OFH CSB-EP878016OFH CSB-BP878016OFH CSB-MP878016OFH CSB-EP878016OFH-B	Recombinant Oryzias latipes G2/mitotic-specific cyclin-B1 (ccnb1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CCNB1 Proteins for Oryzias curvinotus (Hynann ricefish) (Aplocheilus curvinotus)

Code	Product Name	Source
CSB-YP880592OCAN CSB-EP880592OCAN CSB-BP880592OCAN CSB-MP880592OCAN CSB-EP880592OCAN-B	Recombinant Oryzias curvinotus G2/mitotic-specific cyclin-B1 (ccnb1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CCNB1 Proteins for Oryzias javanicus (Javanese ricefish) (Aplocheilus javanicus)

Code	Product Name	Source
CSB-YP884091OCAE CSB-EP884091OCAE CSB-BP884091OCAE CSB-MP884091OCAE CSB-EP884091OCAE-B	Recombinant Oryzias javanicus G2/mitotic-specific cyclin-B1 (ccnb1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CCNB1 Proteins for Oryzias luzonensis (Luzon ricefish)

Code	Product Name	Source
CSB-YP887615OCAG CSB-EP887615OCAG CSB-BP887615OCAG CSB-MP887615OCAG CSB-EP887615OCAG-B	Recombinant Oryzias luzonensis G2/mitotic-specific cyclin-B1 (ccnb1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Promotions

Popular Pathways

Apoptosis

Breast Cancer

Autophagy

Hippo Signaling Pathway

Wnt Signaling Pathway

Hippo signaling pathway

TGF-beta signaling pathway

Apoptosis mediated by mitochondria The Overview of Hippo Signaling Pathway The Overview of Autophagy Crosstalk Between Autophagy and Apoptosis The Overview of Wnt Signaling Pathway The Overview of Breast Cancer: Related Signaling Pathways, Therapeutic Targets The overview of TGF-β signaling pathway PI3K-Akt Signaling Pathway and Cancer Apoptosis mediated by endoplasmic reticulum Apoptosisi mediated by death receptor Aesthetic Appreciation of Apoptosis Signal Pathway An Overview of Cell Death: Necrosis and Apoptosis Do You Really Know TGF-β Superfamily? Double-Edged Sword: TGF-β The Overview of PI3-Alt Signaling Pathway How to Inquire and Utilize the Signal Pathway on KEGG LPS/TLR4 Signal Transduction Pathway Epigenetic Histone Modifications Pathway What A Paradoxical TNF Signaling Pathway-Based on Different Receptors The Overview of Fc Receptors- Classification, Related Signaling Pathways and Application

CCNB1

Popular Product: