CD5

CD5, or LEU1, is a crucial glycoprotein predominantly found on the surface of T lymphocytes. It serves as a vital marker for T cell identity and is deeply ingrained in the core processes of T cell activation, the balance of apoptosis, and signal transduction. CD5's unique negative regulatory effect allows T cells to navigate the intricate immune environment, fostering effective immune responses while curbing the onset of autoimmune diseases. Moreover, aberrant CD5 expression is associated with a spectrum of T cell-related conditions, providing a significant foundation for their diagnosis, treatment, and prognosis.