CDS1

CDS1 encodes CTP:phosphocholine cytidylyltransferase 1, a key enzyme in phosphatidylcholine biosynthesis. It catalyzes the conversion of phosphocholine to CDP-choline, regulating membrane lipid homeostasis. Common aliases include PCYT1A. The enzyme is activated by binding to membranes under phosphatidylcholine-deficient conditions, integrating lipid metabolism with cell growth signals.
CDS1 dysfunction links to non-alcoholic fatty liver disease and cancer, where altered phosphatidylcholine synthesis affects membrane integrity and signaling. It interacts with the PI3K/Akt pathway, influencing cell proliferation. Current research explores CDS1 inhibitors as potential therapeutics for metabolic disorders and malignancies, though clinical development remains in preclinical stages.

Popular Product:

CDS1 Antibody (CSB-PA842170LA01HU)

Validated Data

Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA842170LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human stomach tissue using CSB-PA842170LA01HU at dilution of 1:100

Immunofluorescent analysis of Hela cells using CSB-PA842170LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

The following CDS1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CDS1 Antibodies

CDS1 Proteins

CDS1 Antibodies

CDS1 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA842170LA01HU	CDS1 Antibody	Human	ELISA, IHC, IF

CDS1 Antibodies for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Species Reactivity	Application
CSB-PA516900XA01DOA	CDS1 Antibody	Arabidopsis thaliana	ELISA, WB (ensure identification of antigen)

CDS1 Antibodies for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA334390XA01SVG	CDS1 Antibody	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ELISA, WB (ensure identification of antigen)

CDS1 Antibodies for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Species Reactivity	Application
CSB-PA600600XA01SXV	cds1 Antibody	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)	ELISA, WB (ensure identification of antigen)

CDS1 Antibodies for Solanum tuberosum (Potato)

Code	Product Name	Species Reactivity	Application
CSB-PA516901XA01FIG	CDS1 Antibody	Solanum tuberosum (Potato)	ELISA, WB (ensure identification of antigen)

CDS1 Proteins

CDS1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Code	Product Name	Source
CSB-YP600600SXV CSB-EP600600SXV CSB-BP600600SXV CSB-MP600600SXV CSB-EP600600SXV-B	Recombinant Schizosaccharomyces pombe Serine/threonine-protein kinase cds1 (cds1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CDS1 Proteins for Arabidopsis thaliana (Mouse-ear cress)

Code	Product Name	Source
CSB-CF516900DOA	Recombinant Arabidopsis thaliana Phosphatidate cytidylyltransferase (CDS1)	in vitro E.coli expression system
CSB-YP516900DOA1 CSB-EP516900DOA1 CSB-BP516900DOA1 CSB-MP516900DOA1 CSB-EP516900DOA1-B	Recombinant Arabidopsis thaliana Phosphatidate cytidylyltransferase (CDS1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CDS1 Proteins for Solanum tuberosum (Potato)

Code	Product Name	Source
CSB-CF516901FIG	Recombinant Solanum tuberosum Phosphatidate cytidylyltransferase (CDS1)	in vitro E.coli expression system
CSB-YP516901FIG1 CSB-EP516901FIG1 CSB-BP516901FIG1 CSB-MP516901FIG1 CSB-EP516901FIG1-B	Recombinant Solanum tuberosum Phosphatidate cytidylyltransferase (CDS1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CDS1 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Code	Product Name	Source
CSB-CF334390SVG	Recombinant Saccharomyces cerevisiae Phosphatidate cytidylyltransferase (CDS1)	in vitro E.coli expression system
CSB-YP334390SVG1 CSB-EP334390SVG1 CSB-BP334390SVG1 CSB-MP334390SVG1 CSB-EP334390SVG1-B	Recombinant Saccharomyces cerevisiae Phosphatidate cytidylyltransferase (CDS1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CDS1 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-CF842170HU	Recombinant Human Phosphatidate cytidylyltransferase 1 (CDS1)	in vitro E.coli expression system
CSB-YP842170HU1 CSB-EP842170HU1 CSB-BP842170HU1 CSB-MP842170HU1 CSB-EP842170HU1-B	Recombinant Human Phosphatidate cytidylyltransferase 1 (CDS1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CDS1 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-CF005122MO	Recombinant Mouse Phosphatidate cytidylyltransferase 1 (Cds1)	in vitro E.coli expression system
CSB-YP005122MO1 CSB-EP005122MO1 CSB-BP005122MO1 CSB-MP005122MO1 CSB-EP005122MO1-B	Recombinant Mouse Phosphatidate cytidylyltransferase 1 (Cds1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CDS1 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-CF005122RA	Recombinant Rat Phosphatidate cytidylyltransferase 1 (Cds1)	in vitro E.coli expression system
CSB-YP005122RA1 CSB-EP005122RA1 CSB-BP005122RA1 CSB-MP005122RA1 CSB-EP005122RA1-B	Recombinant Rat Phosphatidate cytidylyltransferase 1 (Cds1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CDS1 Proteins for Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)

Code	Product Name	Source
CSB-YP822127EKH CSB-EP822127EKH CSB-BP822127EKH CSB-MP822127EKH CSB-EP822127EKH-B	Recombinant Encephalitozoon cuniculi Phosphatidate cytidylyltransferase (CDS1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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