CLEC18A encodes the C-type lectin domain family 18 member A, a transmembrane protein with a conserved C-type lectin domain. It participates in innate immunity by recognizing glycosylated ligands on pathogens or altered host cells, triggering signaling cascades that regulate cytokine secretion and immune cell activation, supporting immune surveillance.
Aberrant CLEC18A expression links to inflammatory disorders and certain malignancies, where it may promote tumor invasion or immune evasion. Preclinical research is exploring CLEC18A as a therapeutic target, aiming to develop agents modulating its activity to enhance anti-tumor responses or mitigate inflammatory damage.
Recombinant Human C-type lectin domain family 18 member A (CLEC18A) (CSB-EP005521HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
CLEC18A Antibody (CSB-PA005521LA01HU)
Validated Data
Western blot
All lanes: CLEC18A antibody at 2µg/ml + Mouse stomach tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 50, 12 kDa
Observed band size: 50 kDa
Immunohistochemistry of paraffin-embedded human stomach tissue using CSB-PA005521LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA005521LA01HU at dilution of 1:100
Human C-type lectin domain family 18 member A(CLEC18A) ELISA kit (CSB-EL005521HU)
Validated Data
Code: CSB-EL005521HU
Size: 96T,5×96T,10×96T
Sensitivity: 0.078 ng/mL
Detection Range: 0.312 ng/mL-20 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following CLEC18A reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CLEC18A Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA005521GA01HU | CLEC18A Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA005521LA01HU | CLEC18A Antibody | Human, Mouse | ELISA, WB, IHC |
CLEC18A Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP005521HU CSB-BP005521HU CSB-MP005521HU CSB-EP005521HU-B |
Recombinant Human C-type lectin domain family 18 member A (CLEC18A) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP005521HU | Recombinant Human C-type lectin domain family 18 member A (CLEC18A) | E.coli |
CLEC18A ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL005521HU | Human C-type lectin domain family 18 member A(CLEC18A) ELISA kit | serum, plasma, tissue homogenates | 0.078 ng/mL |