CREB3L2 Research Reagents

Cyclic AMP-responsive element-binding protein 3-like protein 2 is a protein in humans that is encoded by CREB3L2 gene. Transcription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in chondrogenesis by activating the transcription of SEC23A, which promotes the transport and secretion of cartilage matrix proteins, and possibly that of ER biogenesis-related genes (By similarity).

The following CREB3L2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CREB3L2 Antibodies

CREB3L2 Antibodies for Homo sapiens (Human)

CREB3L2 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

CREB3L2 Proteins

CREB3L2 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

CREB3L2 Proteins for Rattus norvegicus (Rat)

CREB3L2 Proteins for Homo sapiens (Human)

CREB3L2 Proteins for Mus musculus (Mouse)

CREB3L2 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

CREB3L2 Proteins for Xenopus laevis (African clawed frog)

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