CT83

CT83, also known as cancer/testis antigen 83 or KK-LC-1, is a protein coding gene primarily expressed in testicular tissue. It is a member of the Cancer/Testis Antigen (CTA) family, which is typically expressed in testicular cells but becomes upregulated in various tumors. CT83 plays a role in tumorigenesis and progression, potentially influencing cell migration, invasion, and proliferation. Its expression is associated with several signaling pathways, including the ERK and HIF-1α pathways, and is linked to diseases such as lung, gastric, breast, and liver cancers. Research into CT83 as a therapeutic target is ongoing, with clinical trials exploring its potential in cancer immunotherapy.