CTNNB1

Catenin beta-1 is a protein in humans that is encoded by CTNNB1 gene. Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion, as component of an E-cadherin

CTNNB1 Antibodies

CTNNB1 Antibodies for Human

CTNNB1 Antibodies for Homo sapiens (Human)

CTNNB1 Proteins

CTNNB1 Proteins for Homo sapiens (Human)

CTNNB1 Proteins for Bos taurus (Bovine)

CTNNB1 Proteins for Rattus norvegicus (Rat)

CTNNB1 ELISA Kit

CTNNB1 ELISA Kit for Homo sapiens (Human)

CTNNB1 ELISA Kit for Mus musculus (Mouse)

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