DBI

DBI protein, also known as diazepam-binding inhibitor, is an endogenous ligand of the benzodiazepine binding site on the GABAA receptor. Its main action mechanism involves modulating the function of the GABAA receptor, thereby influencing the inhibitory neurotransmission mediated by gamma-aminobutyric acid (GABA). It participates in the GABAergic signaling pathway.
Abnormalities in DBI are associated with various diseases, including anxiety disorders and epilepsy. In drug development, agents targeting DBI may be potential candidates for treating these neurological disorders. Some pre - clinical studies have explored the effects of modifying DBI activity, aiming to develop novel therapeutic strategies.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

DBI Antibody (CSB-PA006519HA01HU)

Validated Data

Immunohistochemistry of paraffin-embedded human glioma using CSB-PA006519HA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA006519HA01HU at dilution of 1:100

The following DBI reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

DBI Antibodies

DBI Proteins

DBI Antibodies

DBI Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA006519HB01HU	DBI Antibody, HRP conjugated	Human	ELISA
CSB-PA006519HA01HU	DBI Antibody	Human	ELISA, IHC
CSB-PA006519GA01HU	DBI Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA000798	DBI Antibody	Human	WB, IHC, ELISA
CSB-PA005119	DBI Antibody	Human,Mouse,Rat	WB, ELISA

DBI Antibodies for Drosophila melanogaster (Fruit fly)

Code	Product Name	Species Reactivity	Application
CSB-PA212636XA01DLU	Acbp2 Antibody	Drosophila melanogaster (Fruit fly)	ELISA, WB (ensure identification of antigen)

DBI Antibodies for Rattus norvegicus (Rat)

Code	Product Name	Species Reactivity	Application
CSB-PA006519ZA01RA	Dbi Antibody	Rattus norvegicus	ELISA, WB (ensure identification of antigen)

DBI Antibodies for Mus musculus (Mouse)

Code	Product Name	Species Reactivity	Application
CSB-PA006519ZA01MO	Dbi Antibody	Mus musculus	ELISA, WB (ensure identification of antigen)

DBI Proteins

DBI Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP006519PI CSB-EP006519PI CSB-BP006519PI CSB-MP006519PI CSB-EP006519PI-B	Recombinant Pig Acyl-CoA-binding protein (DBI)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DBI Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-BP006519MO CSB-MP006519MO CSB-EP006519MO-B	Recombinant Mouse Acyl-CoA-binding protein (Dbi)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP006519MO	Recombinant Mouse Acyl-CoA-binding protein (Dbi)	E.coli

DBI Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP006519BO CSB-EP006519BO CSB-BP006519BO CSB-MP006519BO CSB-EP006519BO-B	Recombinant Bovine Acyl-CoA-binding protein (DBI)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DBI Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP006519HU CSB-BP006519HU CSB-MP006519HU CSB-EP006519HU-B	Recombinant Human Acyl-CoA-binding protein (DBI)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP006519HU	Recombinant Human Acyl-CoA-binding protein (DBI)	E.coli

DBI Proteins for Chaetophractus villosus (South American armadillo)

Code	Product Name	Source
CSB-YP006519CHJ CSB-EP006519CHJ CSB-BP006519CHJ CSB-MP006519CHJ CSB-EP006519CHJ-B	Recombinant Chaetophractus villosus Acyl-CoA-binding protein (DBI)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DBI Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP006519RA CSB-BP006519RA CSB-MP006519RA CSB-EP006519RA-B	Recombinant Rat Acyl-CoA-binding protein (Dbi)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP006519RA	Recombinant Rat Acyl-CoA-binding protein (Dbi)	E.coli

DBI Proteins for Anas platyrhynchos (Mallard) (Anas boschas)

Code	Product Name	Source
CSB-YP006519BZD CSB-EP006519BZD CSB-BP006519BZD CSB-MP006519BZD CSB-EP006519BZD-B	Recombinant Anas platyrhynchos Acyl-CoA-binding protein (DBI)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DBI Proteins for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Source
CSB-YP851946RB CSB-EP851946RB CSB-BP851946RB CSB-MP851946RB CSB-EP851946RB-B	Recombinant Rabbit Acyl-CoA-binding protein (DBI)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DBI Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Source
CSB-YP866124DO CSB-EP866124DO CSB-BP866124DO CSB-MP866124DO CSB-EP866124DO-B	Recombinant Dog Acyl-CoA-binding protein (DBI)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

DBI Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-YP882464CH CSB-EP882464CH CSB-BP882464CH CSB-MP882464CH CSB-EP882464CH-B	Recombinant Chicken Acyl-CoA-binding protein (DBI)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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DBI

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