ER degradation-enhancing alpha-mannosidase-like protein 1is a protein in humans that is encoded by EDEM1 gene. Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.
The following EDEM1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
EDEM1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA838793LA01HU | EDEM1 Antibody |
Human | ELISA, IHC |
CSB-PA838793LB01HU | EDEM1 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA838793LC01HU | EDEM1 Antibody, FITC conjugated |
Human | |
CSB-PA838793LD01HU | EDEM1 Antibody, Biotin conjugated |
Human | ELISA |
EDEM1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP838793HU CSB-EP838793HU CSB-BP838793HU CSB-MP838793HU CSB-EP838793HU-B |
Recombinant Human ER degradation-enhancing alpha-mannosidase-like 1 (EDEM1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
EDEM1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP852892MO CSB-EP852892MO CSB-BP852892MO CSB-MP852892MO CSB-EP852892MO-B |
Recombinant Mouse ER degradation-enhancing alpha-mannosidase-like 1 (Edem1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |